Korean J Neurotrauma.  2015 Oct;11(2):135-138. 10.13004/kjnt.2015.11.2.135.

Lytic Complications after Skull Reconstruction Using GeneX(R)

• Park JH
• Suh SJ
• Lee YS
• Lee JH
• Ryu KY
• Kang DG

• KMID: 2378272
• DOI: http://doi.org/10.13004/kjnt.2015.11.2.135

Abstract

Multiple methods and materials are available for bone defect reconstruction. Bone graft substitute is one of the materials used for reconstruction of bone defect and have been widely used recently. This report describes some cases about complications related to GeneX(R) which is introduced as mixture of calcium sulfate and beta-tricalcium phosphate at manufacturer's official web site. It informed of 3 patients who suffered wound inflammation, serous cyst after using GeneX(R) for reconstructing skull defect.

Keyword

Skull defect; Bone substitutes; Postoperative complications

MeSH Terms

Bone Substitutes
Calcium Sulfate
Humans
Inflammation
Postoperative Complications
Skull*
Transplants
Wounds and Injuries
Bone Substitutes
Calcium Sulfate

Figure

• 

  FIGURE 1 A: Brain MRI shows round cyst on right parietal lobe (asterisk). B: Brain computed tomography shows loss of the reconstructed material along the inner side (black arrowheads). C: Photograph shows turbid fluid with multiple tiny particles (black arrows). D: Inflammatory cells are mainly composed of neutrophil (hematoxylin-eosin, original magnification, ×400).

• 

  FIGURE 2 A: Swelling on previous operation site is seen (dotted line). B: Follow up brain computed tomography shows cystic lesion instead of reconstructed material (white arrowheads). C: Photograph shows cyst which is enclosed in a whitish membrane and collected turbid fluid with multiple tiny particles inside (black arrowheads). D: Lymphocytes are scattered (hematoxylin-eosin, original magnification, ×400).

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