Gut Liver.  2015 Nov;9(6):784-790. 10.5009/gnl14272.

Measurement of Intrahepatic Pressure during Microwave Ablation in an Ex Vivo Bovine Liver Model

• Kim HJ
• Rhim H
• Lee MW
• Jeong WK

• KMID: 2377937
• DOI: http://doi.org/10.5009/gnl14272

Abstract

BACKGROUND/AIMS
We experimented with different ablation methods and two types of microwave antennas to determine whether microwave ablation (MWA) increases intrahepatic pressure and to identify an MWA protocol that avoids increasing intrahepatic pressure.
METHODS
MWA was performed using either a single-step standard ablation or a stepwise increment ablation paired with either a 16-gauge (G) 2-cm antenna or a 14G 4-cm antenna. We compared the maximum pressures and total ablation volumes.
RESULTS
The mean maximum intrahepatic pressures and ablation volumes were as follows: 16G single-step: 37+/-33.4 mm Hg and 4.63 cm3; 16G multistep: 31+/-18.7 mm Hg and 3.75 cm3; 14G single-step: 114+/-45.4 mm Hg and 15.33 cm3; and 14G multistep: 106+/-43.8 mm Hg and 10.98 cm3. The intrahepatic pressure rose during MWA, but there were no statistically significant differences between the single and multistep methods when the same gauge antennae were used. The total ablation volume was different only in the 14G groups (p<0.05).
CONCLUSIONS
We demonstrated an increase in intrahepatic pressure during MWA. The multistep method may be used to prevent increased intrahepatic pressure after applying the proper power.

Keyword

Microwave ablation; Intrahepatic pressure; Ex vivo; Liver

MeSH Terms

Ablation Techniques/instrumentation/*methods
Animals
Cattle
Liver/*physiology/surgery
Medical Illustration
*Microwaves
Models, Animal
*Pressure