Int J Arrhythm.  2017 Mar;18(1):16-26. 10.18501/arrhythmia.2017.002.

The Impact of the CHAâ‚‚DSâ‚‚-VASc Score on Recurrence of Atrial Fibrillation after a Single Catheter Ablation and Atrial Remodeling in Patients with Non-Valvular Atrial Fibrillation

• Lee CH
• Lee SH
• Park KH
• Shin DG

• KMID: 2377062
• DOI: http://doi.org/10.18501/arrhythmia.2017.002

Abstract

BACKGROUND AND OBJECTIVES
This study aimed to evaluate the impact of the CHAâ‚‚DSâ‚‚-VASc score on atrial fibrillation (AF) recurrence after a single catheter ablation procedure in patients with non-valvular AF. We also investigated the correlation between CHAâ‚‚DSâ‚‚-VASc score and atrial substrate.
SUBJECTS AND METHODS
This study evaluated 151 patients who underwent catheter ablation of non-valvular AF. The study population was stratified into group 1 (<2, n=72) and group 2 (≥2, n=79) by CHA₂DS₂-VASc score. The CHA₂DS₂-VASc score was analyzed as a continuous and categorical value for evaluating its impact on AF recurrence after catheter ablation. The left atrial voltage data were analyzed by the categorical values of this score.
RESULTS
Post-ablation recurrence (31.6% vs. 18.1%, p=0.046) was observed more frequently in group 2. The mean area of the lowvoltage zone was 75.64±24.81 cm² and 94.44±28.09 cm² in groups 1 and 2, respectively (p=0.005). The left atrial mean voltage in group 2 was 0.99±0.31 mV, significantly lower than that (1.49±0.67 mV, p=0.001) in group 1. The CHAâ‚‚DSâ‚‚-VASc score was the independent predictor with a modest predictive value for AF recurrence after catheter ablation.
CONCLUSION
Our study showed that CHAâ‚‚DSâ‚‚-VASc score was associated with atrial remodeling and could be useful in stratifying post-ablation recurrence in patients with non-valvular AF.

Keyword

Atrial Fibrillation; Catheter Ablation; Recurrence; Atrial Remodeling

MeSH Terms

Atrial Fibrillation*
Atrial Remodeling*
Catheter Ablation*
Catheters*
Humans
Recurrence*