J Stroke.
2016 May;18(2):129-137. 10.5853/jos.2016.00234.
The Mechanism of and Preventive Therapy for Stroke in Patients with Atrial Fibrillation
- Affiliations
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- 1Cardiology Division, Korea University Medical Center, Seoul, Korea. yhkmd@unitel.co.kr
- KMID: 2285606
- DOI: http://doi.org/10.5853/jos.2016.00234
Abstract
- Atrial fibrillation is a major cardiac cause of stroke, and a pathogenesis involving thrombus formation in patients with atrial fibrillation is well established. A strategy for rhythm control that involves catheter ablation and anticoagulation therapy is evolving. A strategy for rhythm control that restores and maintains sinus rhythm should reduce the risk of ischemic stroke that is associated with atrial fibrillation; however, this is yet to be proven in large-scale randomized controlled trials. This paper reviews the emerging role of rhythm control therapy for atrial fibrillation to prevent stroke.
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