Korean J Med.  2017 Feb;92(1):45-52. 10.3904/kjm.2017.92.1.45.

Comparison of Peritoneal Dialysis and Hemodialysis Patients Following Extended Treatment Periods in a Single Center

• Kim JM
• Lee SJ
• Seo DK
• Lee KY
• Ryu SR
• Lee SY

• KMID: 2376943
• DOI: http://doi.org/10.3904/kjm.2017.92.1.45

Abstract

BACKGROUND/AIMS
Improvements in dialysis therapies and patient care are leading to more patients receiving dialysis for longer periods of time. Survival rates with peritoneal dialysis (PD) are superior to those with hemodialysis (HD) during the initial 2-3 years; however, data comparing the outcomes of these two methods are lacking. Thus, we performed a retrospective study of patients treated with dialysis for longer than 3 years to investigate patient condition according to mode of dialysis.
METHODS
A total of 80 patients currently being treated by dialysis for at least 36 months at the Eulji Medical Center were included in this study. Patients' laboratory data and admissions histories over the prior 3 years were reviewed. Dialysis adequacy, body composition, and cytokine levels were quantified.
RESULTS
A total of 39 PD and 41 HD patients, with no difference in mean age or gender, were compared. Regarding dialysis adequacy, 97.5% of HD patients met the criterion of 1.2 Kt/V or higher, whereas only 58% of PD patients satisfied the required weekly Kt/V of 1.7. Inflammatory cytokines were significantly elevated in PD patients; however, PD patients with adequate dialysis expressed the same inflammatory cytokines as HD patients.
CONCLUSIONS
The delivery of adequate dialysis to PD patients over extended periods of time is difficult. Thus, more rigorous management of PD patients is required to avoid insufficient dialysis and inflammation.

Keyword

Renal dialysis; Peritoneal dialysis; Cytokines

MeSH Terms

Body Composition
Cytokines
Dialysis
Humans
Inflammation
Patient Care
Peritoneal Dialysis*
Renal Dialysis*
Retrospective Studies
Survival Rate
Cytokines