Prog Med Phys.  2016 Dec;27(4):232-235. 10.14316/pmp.2016.27.4.232.

Development Treatment Planning System Based on Monte-Carlo Simulation for Boron Neutron Capture Therapy

• Kim MS
• Kubo K
• Monzen H
• Yoon DK
• Shin HB
• Kim S
• Suh TS

• KMID: 2376557
• DOI: http://doi.org/10.14316/pmp.2016.27.4.232

Abstract

The purpose of this study is to develop the treatment planning system (TPS) based on Monte-Carlo simulation for BNCT. In this paper, we will propose a method for dose estimation by Monte-Carlo simulation using the CT image, and will evaluate the accuracy of dose estimation of this TPS. The complicated geometry like a human body allows defining using the lattice function in MCNPX. The results of simulation such as flux or energy deposition averaged over a cell, can be obtained using the features of the tally provided by MCNPX. To assess the dose distribution and therapeutic effect, dose distribution was displayed on the CT image, and dose volume histogram (DVH) was employed in our developed system. The therapeutic effect can be efficiently evaluated by these evaluation tool. Our developed TPS could be effectively performed creating the voxel model from CT image, the estimation of each dose component, and evaluation of the BNCT plan.

Keyword

BNCT; Monte Carlo; MCNPX; Treatment planning system

MeSH Terms

Boron Neutron Capture Therapy*
Boron*
Human Body
Methods
Boron

Figure

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  Fig. 1 Schematic of Monte-Carlo simulation.

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  Fig. 2 Creating the voxel model from the patients' CT image for dose calculation. (a) original patients' CT image and (b) the reconstructed voxel model.

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  Fig. 3 Depth dose for each dose component along the beam centerline.

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  Fig. 4 Dose distribution on the patients' CT image.

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  Fig. 5 Dose volume histogram (DVH) for BNCT.

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