Yeungnam Univ J Med.  1988 Dec;5(2):79-86. 10.12701/yujm.1988.5.2.79.

The Effect of Exercise on the Conversion Rate of Ingested Glucose to Glycogen in the Hindlimb Skeletal Muscles in Rats

• Jung KH
• Kim JY
• Kim YW
• Lee SK

• KMID: 2376239
• DOI: http://doi.org/10.12701/yujm.1988.5.2.79

Abstract

In the present study the effect of exercise on the conversion rate of ingested glucose to glycogen in the different types of hindlimb skeletal muscles in Sprague-Dawley male rats was studied. The amounts of synthetized glycogen from ingested glucose of fast-twitch white (WV), fast-twitch red (RV), mixed type of fast-twitch white and red (EDL), and slow-twitch (SOL) muscles were determined at 30 and 90 min. after ingestion of 25% glucose solution which contained 14C-glucose(2 ml(luCi)/100gm B.W.) in control and exercise loaded rats. The result was summarized as follows: The about 55% at 30 min. and 70% at 90 min. after glucose ingestion were absorbed from gastrointestinal tract. This result shows no effects of exercise on absorption rate from gastrointestinal tract. The amount of synthetized glycogen of SOL from ingested glucose at 30 and 90 min. after glucose ingestion were highest, whether WV were lowest in hindlimb skeletal muscles in control and exercise loaded rats. In the exercise loaded rats, the amounts of synthetized glycogen of SOL, RV, and EDL at 90 min. after glucose ingestion was much higher than control rats, but not different in WV between exercise-loaded and control rats. At 30 min. after glucose ingestion, only SOL of exercise loaded rats was higher than control rats. In the control rat, the synthesis of glycogen was almost completed during initial 30 minutes. On the other hand, in the exercise loaded rat, except WV was opposite result of control rats, i.e., amounts of synthetized glycogen were major during late period. The amount of synthetized glycogen of liver at 30 and 90 min. after glucose ingestion in exercise loaded rats was higher than control rats. The rate of glycogen synthesis in control and exercise loaded rats were higher between 30-90 minute than initial 30 minutes.

MeSH Terms

Absorption
Animals
Eating
Gastrointestinal Tract
Glucose*
Glycogen*
Hand
Hindlimb*
Humans
Liver
Male
Muscle, Skeletal*
Muscles
Rats*
Rats, Sprague-Dawley
Glucose
Glycogen