Korean J Intern Med.  2016 Jan;31(1):54-64. 10.3904/kjim.2016.31.1.54.

Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding

• Lee YJ
• Min BR
• Kim ES
• Park KS
• Cho KB
• Jang BK
• Chung WJ
• Hwang JS
• Jeon SW

• KMID: 2373773
• DOI: http://doi.org/10.3904/kjim.2016.31.1.54

Abstract

BACKGROUND/AIMS
Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition.
METHODS
A prospective observational study was conducted at a single hospital between April 2010 and November 2012, and 336 patients with symptoms and signs of gastrointestinal bleeding were consecutively enrolled. Clinical characteristics and endoscopic findings were reviewed to identify potential factors associated with 30-day mortality.
RESULTS
Overall, 184 patients were included in the study (men, 79.3%; mean age, 59.81 years), and 16 patients died within 30 days (8.7%). Multivariate analyses revealed that comorbidity of diabetes mellitus (DM) or metastatic malignancy, age > or = 65 years, and hypotension (systolic pressure < 90 mmHg) during hospitalization were significant predictive factors of 30-day mortality.
CONCLUSIONS
Comorbidity of DM or metastatic malignancy, age > or = 65 years, and hemodynamic instability during hospitalization were predictors of 30-day mortality in patients with NVUGIB. These results will help guide the management of patients with this condition.

Keyword

Gastrointestinal hemorrhage; Mortality; Prognosis; Comorbidity

MeSH Terms

Adult
Age Factors
Aged
Chi-Square Distribution
Comorbidity
Diabetes Mellitus/mortality
Endoscopy, Gastrointestinal
Female
Gastrointestinal Hemorrhage/diagnosis/*mortality/physiopathology/therapy
Hemodynamics
Hospital Mortality
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Neoplasm Metastasis
Odds Ratio
Predictive Value of Tests
Prospective Studies
Republic of Korea
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome