Ann Lab Med.  2017 Jan;37(1):71-73. 10.3343/alm.2017.37.1.71.

A Family With a Hemoglobin E Variant Including a Thai Immigrant Woman in Korea

• Jahng J
• Yoon KH

• KMID: 2373618
• DOI: http://doi.org/10.3343/alm.2017.37.1.71

Abstract

No abstract available.

MeSH Terms

Base Sequence
DNA/metabolism
Emigration and Immigration
Female
Hemoglobin E/*genetics
Homozygote
Humans
Polymerase Chain Reaction
Republic of Korea
Sequence Analysis, DNA
Thailand
DNA
Hemoglobin E

Figure

• 

  Fig. 1 Sanger sequencing of the HBB gene, alkaline Hb electrophoresis (see Table 1) and peripheral blood smear (Wright stain, ×1,000) in the Hb E family. (A) Normal findings. (B) Homozygous Hb E (c.79G>A; p.Glu27Lys) variant, increased Hb F and Hb A2 fractions, and many target cells. (C) Heterozygous Hb E, increased Hb A2 and some target cells. (D) Heterozygous Hb E, increased Hb F and Hb A2, and some target cells.

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