Ann Lab Med.  2016 May;36(3):281-283. 10.3343/alm.2016.36.3.281.

Two Cases of Clostridium tertium Infection and Successful Identification of the Organism by Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry Analysis

Affiliations
  • 1Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan. jyumiko@hiroshima-u.ac.jp
  • 2Section of Infection Diseases, Laboratory Division of Clinical Support, Hiroshima University Hospital, Hiroshima, Japan.
  • 3Research Facility, Hiroshima University Faculty of Dentistry, Hiroshima, Japan.
  • 4Division of Laboratory Medicine, Hiroshima University Hospital, Hiroshima, Japan.
  • 5Department of Infectious Diseases, Hiroshima University Hospital, Hiroshima, Japan.

Abstract

No abstract available.


MeSH Terms

Anti-Bacterial Agents/pharmacology/therapeutic use
Bacteremia/*diagnosis/drug therapy/microbiology
Clostridium tertium/drug effects/isolation & purification/*metabolism
Humans
Male
Microbial Sensitivity Tests
Middle Aged
*Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Anti-Bacterial Agents

Figure

  • Fig. 1 Light microscope observation of Gram stain preparations. (A) Gram stain of aerobic blood cultures showed Gram-negative bacilli (×1,000). (B) Gram stain of colonies on Brucella HK agar plates showed an oval spore on the end of gram-variable bacilli (×1,000).


Reference

1. Miller DL, Brazer S, Murdoch D, Reller LB, Corey GR. Significance of Clostridium tertium bacteremia in neutropenic and nonneutropenic patients: review of 32 cases. Clin Infect Dis. 2001; 32:975–978. PMID: 11247721.
2. Steyaert S, Peleman R, Vaneechoutte M, De Baere T, Claeys G, Verschraegen G. Septicemia in neutropenic patients infected with Clostridium tertium resistant to cefepime and other expanded-spectrum cephalosporins. J Clin Microbiol. 1999; 37:3778–3779. PMID: 10523601.
3. Speirs G, Warren RE, Rampling A. Clostridium tertium septicemia in patients with neutropenia. J Infect Dis. 1988; 158:1336–1340. PMID: 3198941.
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