Clin Mol Hepatol.  2016 Dec;22(4):503-508. 10.3350/cmh.2016.0077.

Primary adenosquamous carcinoma of the liver: a case report

• Nam KH
• Kim JY

• KMID: 2373156
• DOI: http://doi.org/10.3350/cmh.2016.0077

Abstract

Adenosquamous carcinoma of the liver is a rare variant of cholangiocarcinoma. It is known to be a highly aggressive tumor with a poor prognosis, but its pathogenesis remains unclear owing to limited data in the literature. We report a case of 56-year-old woman who presented with a 1-week history of epigastric pain. Magnetic resonance imaging revealed a 6.5-cm ill-defined mass with low signal intensity in the left lobe of the liver, which was suspicious of cholangiocarcinoma. The patient underwent left hemihepatectomy. Microscopically, the tumor consisted of malignant glandular and squamous components and staged as pT2aN1. Despite postoperative chemoradiation, the patient had recurrence 8 months after surgery.

Keyword

Adenosquamous carcinoma; Liver; Cholangiocarcinoma; Pathology

MeSH Terms

Abdomen/diagnostic imaging
Carcinoma, Adenosquamous/diagnostic imaging/*pathology
Cholangiopancreatography, Endoscopic Retrograde
Female
Gallstones/surgery
Humans
Liver Neoplasms/diagnostic imaging/*pathology
Middle Aged
Sphincterotomy, Endoscopic
Tomography, X-Ray Computed