Yeungnam Univ J Med.  1984 Dec;1(1):101-106. 10.12701/yujm.1984.1.1.101.

The Effect of Hypobaric Priming Solutions on Extracorporeal Circulation during Open Heart Surgery

• Song SO
• Suh JK
• Kim HD

• KMID: 2372982
• DOI: http://doi.org/10.12701/yujm.1984.1.1.101

Abstract

Before beginning the extracorporeal circulation, perfusionists should supply oxygen into the oxygenator and establish blood flow through the blood line of the heart-lung machine. But these manipulation can induce severe hypocarbic state of priming solutions due to wash out of CO2 gas in the solution. This study was carried out to examine the relationship of blood gas changes between hypocarbic priming solutions and body circulation in 15 patients undergoing open heart surgery with extracorporeal circulation. PaCOâ‚‚, pH, buffer base and PaO2 were measured from priming solutions before and 15 minutes after the extracorporeal circulation. The results were as follows; 1) Before the extracorporeal circulation, mean PaCOâ‚‚ level was 12.1±7.8 mmHg in the priming solution. However, 15 minutes after extracorporeal circulation, the PaCOâ‚‚ level was maintained at 35.7±5.7 mmHg. 2) pH in the priming solution was variable from 6.93 to 7.99 (mean 7.45±0.29), but after 15 minutes it was ranged from 7.28 to 7.42 (mean 7.35±0.05). 3) Mean buffer base level in the priming solution was 7.9±3.5 mmol/l. but after 15 minutes, it was 19.6±1.2 mmol/l. 4) Mean PaOâ‚‚ level in the priming solution was 667.1±45.6 mmHg, but after 15 minutes, it was 280.7±131.7 mmHg.

MeSH Terms

Extracorporeal Circulation*
Heart*
Heart-Lung Machine
Humans
Hydrogen-Ion Concentration
Oxygen
Oxygenators
Thoracic Surgery*
Oxygen