J Korean Gastric Cancer Assoc.  2005 Mar;5(1):47-51.

A Case of Eosinophilic Gastritis Mimicking Borrmann Type-4 Advanced Gastric Cancer

• Shin HW
• Suh BJ
• Yu HJ
• Lee HK
• Kim JP

Abstract

Eosinophilic gastroenteritis is a rare clinicopathologic entity of unknown etiology with a variety of digestive symptoms. The pathogenesis is poorly understood. Diagnostic criteria include demonstration of eosinophilic infiltration of the affected bowel wall, lack of evidence of extraintestinal disease, and exclusion of various disorders that could mimic similar conditions. The disease might involve any area of the gastrointestinal tract from the esophagus to the rectum, but the stomach and the proximal small bowel are most commonly affected. The clinical features depend on which layer and site are involved. We report the case of a 59-year-old male patient with a 3-week history of post-prandial vomiting with malnutrition and weight loss. An abdominopelvic CT showed a gastric outlet obstruction with diffuse wall thickening, as with linitis plastica. Three gastrofiberscopic biopsies showed chronic gastritis. We carried out a radical total gastrectomy with D2 lymph node dissection. The pathologic report revealed a mural type eosinophilic gastritis with a marked hypertrophic scar formation at the proper muscle layer. We report this case with a brief review of the literature.

Keyword

Borrman type-4 stomach cancer; Eosinophilic gastroenteritis

MeSH Terms

Biopsy
Cicatrix, Hypertrophic
Eosinophils*
Esophagus
Gastrectomy
Gastric Outlet Obstruction
Gastritis*
Gastroenteritis
Gastrointestinal Tract
Humans
Linitis Plastica
Lymph Node Excision
Male
Malnutrition
Middle Aged
Rectum
Stomach
Stomach Neoplasms*
Vomiting
Weight Loss