J Gastric Cancer.  2016 Mar;16(1):43-50. 10.5230/jgc.2016.16.1.43.

Low Serum Albumin Level, Male Sex, and Total Gastrectomy Are Risk Factors of Severe Postoperative Complications in Elderly Gastric Cancer Patients

• Kang SC
• Kim HI
• Kim MG

• KMID: 2372552
• DOI: http://doi.org/10.5230/jgc.2016.16.1.43

Abstract

PURPOSE
It is well known that old age is a risk factor for postoperative complications. Therefore, this study aimed to explore the risk factors for poor postoperative surgical outcomes in elderly gastric cancer patients.
MATERIALS AND METHODS
Between January 2006 and December 2015, 247 elderly gastric cancer patients who underwent curative gastrectomy were reviewed. In this study, an elderly patient was defined as a patient aged ≥65 years. All possible variables were used to explore the risk factors for poor early surgical outcomes in elderly gastric cancer patients.
RESULTS
Based on multivariate analyses of preoperative risk factors, preoperative low serum albumin level (<3.5 g/dl) and male sex showed statistical significance in predicting severe postoperative complications. Additionally, in an analysis of surgery-related risk factors, total gastrectomy was a risk factor for severe postoperative complications.
CONCLUSIONS
Our study findings suggest that low serum albumin level, male sex, and total gastrectomy could be risk factors of severe postoperative complications in elderly gastric cancer patients. Therefore, surgeons should work carefully in cases of elderly gastric cancer patients with low preoperative serum albumin level and male sex. We believe that efforts should be made to avoid total gastrectomy in elderly gastric cancer patients.

Keyword

Stomach neoplasms; Aged; Risk factors; Postoperative complications

MeSH Terms

Aged*
Gastrectomy*
Humans
Male*
Multivariate Analysis
Postoperative Complications*
Risk Factors*
Serum Albumin*
Stomach Neoplasms*
Serum Albumin

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