J Gastric Cancer.  2014 Jun;14(2):138-141.

Gastric Metastasis from Ovarian Cancer Presenting as a Submucosal Tumor: A Case Report

• Kim EY
• Park CH
• Jung ES
• Song KY

Abstract

Gastric metastasis from ovarian cancer is rarely reported worldwide. In Korea, only 2 such cases have been reported. Here we report a case of a 58-year-old woman with metastatic gastric cancer from an ovarian adenocarcinoma. Endoscopic examination showed that the cancer presented as a submucosal tumor without ulceration. A subsequent gastrectomy confirmed the diagnosis of metastatic ovarian serous adenocarcinoma.

Keyword

Ovary; Cancer; Stomach; Metastasis; Submucosal tumor

MeSH Terms

Adenocarcinoma
Diagnosis
Female
Gastrectomy
Humans
Korea
Middle Aged
Neoplasm Metastasis*
Ovarian Neoplasms*
Ovary
Stomach
Stomach Neoplasms
Ulcer

Figure

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  Fig. 1 Gastroduodenoscopy findings. (A) The gastroduodenoscopy showed a 2 cm submucosal tumor with erosion on the greater curvature of the antrum. (B) The mass was a heterogeneous low-echogenic lesion showing irregularity at the propria muscle layer.

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  Fig. 2 Computed tomography (CT) findings. A CT scan indicated focal thickening and mass formation in the greater curvature of the gastric body (arrow) as well as multiple enlarged lymph nodes along the greater curvature of the stomach.

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  Fig. 3 Gross findings (A) and cut sections (B). A 3.5 × 3.0 cm tumor was situated over the submucosa and muscularis propria in the stomach. The mucosa of the tumor was intact.

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  Fig. 4 Microscopic findings. (A, B) Microscopically, infiltration of metastatic serous adenocarcinoma cells into normal gastric tissues was observed. (A: H&E, ×40; B: H&E, ×200). (C) The tumor cells' immunohistochemical staining value was WT-1 positive (×200). (D) The tumor cells' immunohistochemical staining value was GCDPF-15 negative (×200).

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