J Gastric Cancer.  2012 Jun;12(2):55-62.

Comparisons of Gastric Cancer Treatments: East vs. West

• Bickenbach K
• Strong VE

Abstract

There has been a large amount of speculation concerning the differences in the outcomes in patients who have gastric cancer in the Eastern and Western worlds. The differences in biology, surgical and adjuvant treatment have been used to explain such differences. There are clear differences observed in the histology (diffuse vs. intestinal), tumor location (proximal vs. distal), environmental exposures, dietary factors and Helicobacter pylori status. A higher incidence of gastric cancer in the East has led to screening programs, and leading to an earlier stage at presentation. Surgical treatment differs in that the extended lymph node dissection is routinely practiced in the Asian countries. Additionally, different adjuvant therapeutic regimens are used in both regions. The purpose of this review is to describe the differences in both presentation and treatment between the East and the West.

Keyword

Gastric Cancer; Gastric adenocarcinoma; Western experience; Eastern experience; Gastric cancer survival

MeSH Terms

Asian Continental Ancestry Group
Biology
Environmental Exposure
Helicobacter pylori
Humans
Incidence
Lymph Node Excision
Mass Screening
Stomach Neoplasms
Western World

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