J Gastric Cancer.  2015 Mar;15(1):58-63. 10.5230/jgc.2015.15.1.58.

Gastric Duplication Cysts in Adults: A Report of Three Cases

• Kim SM
• Ha MH
• Seo JE
• Kim JE
• Min BH
• Choi MG
• Lee JH
• Kim KM
• Choi DI
• Sohn TS
• Bae JM
• Kim JJ
• Kim S
• Lee JH

• KMID: 2372372
• DOI: http://doi.org/10.5230/jgc.2015.15.1.58

Abstract

Gastric duplication cyst is a rare congenital anomaly of the gastrointestinal tract and is especially uncommon in adults. Most cases in adults are discovered incidentally on radiological examination or gastric endoscopy. Accurate diagnosis of these cysts before resection is difficult. Differential diagnoses are varied. Malignant transformation of a gastric duplication cyst is very rare. We present three cases of asymptomatic noncommunicating gastric duplication cysts in adults.

Keyword

Stomach; Cyst; Surgery

MeSH Terms

Adult*
Diagnosis
Diagnosis, Differential
Endoscopy
Gastrointestinal Tract
Humans
Stomach

Figure

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  Fig. 1 (A) Esophagogastroduodenoscopy shows a protruding subepithelial lesion. (B) Endoscopic ultrasonography shows a homogeneous hypoechoic lesion located outside the gastric wall layers. (C) Computed tomography shows a well-marginated cystic lesion, suspected to be a bronchogenic cyst or gastrointestinal stromal tumor. (D) Magnetic resonance imaging shows a well-marginated cystic lesion, suspected to be a bronchogenic cyst or gastrointestinal stromal tumor. (E) Microscopic examination revealed that the submucosal mass was a cystic lesion (H&E, ×1; slide scan). (F) Histologically, the mass consisted of the mucosa, subepithelial connective tissue, and several layers of smooth muscle bundles with multifocal macrophage accumulation (H&E, ×80).

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  Fig. 2 (A) Esophagogastroduodenoscopy shows an elevated lesion covered with smooth normal mucosa and located just below the esophagogastric junction. (B) Abdominal computed tomography revealed a submucosal cystic tumor. (C) Microscopic examination revealed a cyst embedded within the gastric muscular layer and showed that this cyst did not communicate with the gastric lumen (H&E, ×1; slide scan). (D) The mucosa was lined with ciliated pseudostratified columnar epithelium with well-developed muscle layers (H&E, ×200).

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  Fig. 3 (A) Endoscopy show a protruding mass at the fundus of the stomach. (B) Computed tomography shows a dumbbell-shaped mass at the gastric fundus, consistent with a submucosal or neurogenic tumor. (C) Laparoscopy shows a protruding mass at the fundus of the stomach. (D) The round mass was filled with a mucus-like yellowish fluid. (E) Microscopic examination revealed a cystic lesion surrounded by a thickened gastric muscular layer (H&E, ×1; slide scan). (F) The cyst was lined with gastric foveolar epithelium with pyloric glands and two or three complete layers of smooth muscle bundles (H&E, ×100).

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