J Gastric Cancer.  2014 Mar;14(1):54-57.

Gastric Carcinoma with Bone Marrow Metastasis: A Case Series

• Ekinci AS
• Bal O
• Ozatli T
• Turker I
• Esbah O
• Demirci A
• Budakoglu
• Arslan UY
• Eraslan E
• Oksuzoglu

Abstract

Gastric cancer is a major cause of cancer-related mortality. At the time of diagnosis, majority of the patients usually have unresectable or metastatic disease. The most common sites of metastases are the liver and the peritoneum, but in the advanced stages, there may be metastases to any region of the body. Bone marrow is an important metastatic site for solid tumors, and the prognosis in such cases is poor. In gastric cancer cases, bone marrow metastasis is usually observed in younger patients and in those with poorly differentiated tumors. Prognosis is worsened owing to the poor histomorphology as well as the occurrence of pancytopenia. The effect of standard chemotherapy is unknown, as survival is limited to a few weeks. This report aimed to evaluate 5 gastric cancer patients with bone marrow metastases to emphasize the importance of this condition.

Keyword

Stomach neoplasms; Bone marrow metastasis; Poor prognosis

MeSH Terms

Bone Marrow*
Diagnosis
Drug Therapy
Humans
Liver
Mortality
Neoplasm Metastasis*
Pancytopenia
Peritoneum
Prognosis
Stomach Neoplasms

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