Korean J Crit Care Med.  2017 Feb;32(1):52-59. 10.4266/kjccm.2016.00885.

Five-year Experience of Extracorporeal Life Support in Emergency Physicians

Affiliations
  • 1Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea. bbukkuk@hanmail.net
  • 2Department of Emergency Medicine, KS Hospital, Gwangju, Korea.

Abstract

BACKGROUND
This study aimed to present our 5-year experience of extracorporeal cardiopulmonary resuscitation (ECPR) performed by emergency physicians.
METHODS
We retrospectively analyzed 58 patients who underwent ECPR between January 2010 and December 2014. The primary parameter analyzed was survival to hospital discharge. The secondary parameters analyzed were neurologic outcome at hospital discharge, cannulation time, and ECPR-related complications.
RESULTS
Thirty-one patients (53.4%) were successfully weaned from extracorporeal membrane oxygenation, and 18 (31.0%) survived to hospital discharge. Twelve patients (20.7%) were discharged with good neurologic outcomes. The median cannulation time was 25.0 min (interquartile range 20.0-31.0 min). Nineteen patients (32.8%) had ECPR-related complications, the most frequent being distal limb ischemia. Regarding the initial presentation, 52 patients (83.9%) collapsed due to a cardiac etiology, and acute myocardial infarction (33/62, 53.2%) was the most common cause of cardiac arrest.
CONCLUSIONS
The survival to hospital discharge rate for cardiac arrest patients who underwent ECPR conducted by an emergency physician was within the acceptable limits. The cannulation time and complications following ECPR were comparable to those found in previous studies.

Keyword

cardiopulmonary resuscitation; extracorporeal membrane oxygenation; heart arrest; treatment outcome

MeSH Terms

Cardiopulmonary Resuscitation
Catheterization
Emergencies*
Extracorporeal Membrane Oxygenation
Extremities
Heart Arrest
Humans
Ischemia
Myocardial Infarction
Retrospective Studies
Treatment Outcome

Reference

References

1. Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010; 121:e46–215.
2. Chen YS, Lin JW, Yu HY, Ko WJ, Jerng JS, Chang WT, et al. Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis. Lancet. 2008; 372:554–61.
Article
3. Cave DM, Gazmuri RJ, Otto CW, Nadkarni VM, Cheng A, Brooks SC, et al. Part 7: CPR techniques and devices: 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2010; 122(18 Suppl 3):S720–8.
4. Morimura N, Sakamoto T, Nagao K, Asai Y, Yokota H, Tahara Y, et al. Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: a review of the Japanese literature. Resuscitation. 2011; 82:10–4.
Article
5. Maekawa K, Tanno K, Hase M, Mori K, Asai Y. Extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest of cardiac origin: a propensity-matched study and predictor analysis. Crit Care Med. 2013; 41:1186–96.
6. Lamhaut L, Jouffroy R, Soldan M, Phillipe P, Deluze T, Jaffry M, et al. Safety and feasibility of prehospital extra corporeal life support implementation by non-surgeons for out-of-hospital refractory cardiac arrest. Resuscitation. 2013; 84:1525–9.
Article
7. Le Guen M, Nicolas-Robin A, Carreira S, Raux M, Leprince P, Riou B, et al. Extracorporeal life support following out-of-hospital refractory cardiac arrest. Crit Care. 2011; 15:R29.
Article
8. Kagawa E, Inoue I, Kawagoe T, Ishihara M, Shimatani Y, Kurisu S, et al. Assessment of outcomes and differences between in- and out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal life support. Resuscitation. 2010; 81:968–73.
Article
9. Thiagarajan RR, Brogan TV, Scheurer MA, Laussen PC, Rycus PT, Bratton SL. Extracorporeal membrane oxygenation to support cardiopulmonary resuscitation in adults. Ann Thorac Surg. 2009; 87:778–85.
Article
10. Massetti M, Tasle M, Le Page O, Deredec R, Babatasi G, Buklas D, et al. Back from irreversibility. extracorporeal life support for prolonged cardiac arrest. Ann Thorac Surg. 2005; 79:178–83.
11. Jacobs I, Nadkarni V, Bahr J, Berg RA, Billi JE, Bossaert L, et al. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries. A statement for healthcare professionals from a task force of the international liaison committee on resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa). Resuscitation. 2004; 63:233–49.
12. Booth CM, Boone RH, Tomlinson G, Detsky AS. Is this patient dead, vegetative, or severely neurologically impaired? Assessing outcome for comatose survivors of cardiac arrest. JAMA. 2004; 291:870–9.
13. Paden ML, Conrad SA, Rycus PT, Thiagarajan RR; ELSO Registry. Extracorporeal life support organization registry report 2012. ASAIO J. 2013; 59:202–10.
Article
14. Chen YS, Chao A, Yu HY, Ko WJ, Wu IH, Chen RJ, et al. Analysis and results of prolonged resuscitation in cardiac arrest patients rescued by extracorporeal membrane oxygenation. J Am Coll Cardiol. 2003; 41:197–203.
Article
15. Haneya A, Philipp A, Diez C, Schopka S, Bein T, Zimmermann M, et al. A 5-year experience with cardiopulmonary resuscitation using extracorporeal life support in non-postcardiotomy patients with cardiac arrest. Resuscitation. 2012; 83:1331–7.
Article
16. Pranikoff T, Hirschl RB, Remenapp R, Swaniker F, Bartlett RH. Venovenous extracorporeal life support via percutaneous cannulation in 94 patients. Chest. 1999; 115:818–22.
Article
17. Roussel A, Al-Attar N, Alkhoder S, Radu C, Raffoul R, Alshammari M, et al. Outcomes of percutaneous femoral cannulation for venoarterial extracorporeal membrane oxygenation support. Eur Heart J Acute Cardiovasc Care. 2012; 1:111–4.
Article
18. Chen YS, Ko WJ, Lin FY. Insertion of percutaneous ECMO cannula. Am J Emerg Med. 2000; 18:184–5.
Article
19. Migliari M, Marcolin R, Avalli L, Bombino M. Percutaneous cannulation: indication, technique, and complications. In: Ecmo-Extracorporeal Life Support in Adults. In : Sangalli F, Patroniti N, Pesenti A, editors. New York: Springer;2014. p. 44.
20. Aziz F, Brehm CE, El-Banyosy A, Han DC, Atnip RG, Reed AB. Arterial complications in patients undergoing extracorporeal membrane oxygenation via femoral cannulation. Ann Vasc Surg. 2014; 28:178–83.
Article
21. Kurusz M, Zwischenberger JB. Percutaneous cardiopulmonary bypass for cardiac emergencies. Perfusion. 2002; 17:269–77.
Article
22. Schwarz B, Mair P, Margreiter J, Pomaroli A, Hoermann C, Bonatti J, et al. Experience with percutaneous venoarterial cardiopulmonary bypass for emergency circulatory support. Crit Care Med. 2003; 31:758–64.
Article
23. Foley PJ, Morris RJ, Woo EY, Acker MA, Wang GJ, Fairman RM, et al. Limb ischemia during femoral cannulation for cardiopulmonary support. J Vasc Surg. 2010; 52:850–3.
Article
24. Conrad SA, Grier LR, Scott LK, Green R, Jordan M. Percutaneous cannulation for extracorporeal membrane oxygenation by intensivists: a retrospective single-institution case series. Crit Care Med. 2015; 43:1010–5.
25. Lee JJ, Han SJ, Kim HS, Hong KS, Choi HH, Park KT, et al. Out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal membrane oxygenation: focus on survival rate and neurologic outcome. Scand J Trauma Resus Emerg Med. 2016; 24:74.
Article
26. Lee DS, Chung CR, Jeon K, Park CM, Suh GY, Song YB, et al. Survival after extracorporeal cardiopulmonary resuscitation on weekends in comparison with weekdays. Ann Thorac Surg. 2016; 101:133–40.
27. Stub D, Bernard S, Pellegrino V, Smith K, Walker T, Sheldrake J, et al. Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial). Resuscitation. 2015; 86:88–94.
Article
28. Johnson NJ, Acker M, Hsu CH, Desai N, Vallabhajosyula P, Lazar S, et al. Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest. Resuscitation. 2014; 85:1527–32.
Article
29. Bellezzo JM, Shinar Z, Davis DP, Jaski BE, Chillcott S, Stahovich M, et al. Emergency physician-initiated extracorporeal cardiopulmonary resuscitation. Resuscitation. 2012; 83:966–70.
Article
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