Ann Dermatol.  2016 Dec;28(6):765-768. 10.5021/ad.2016.28.6.765.

Eccrine Syringofibroadenoma in a Patient with Long-Standing Exfoliative Dermatitis

• Ko EJ
• Park KY
• Kwon HJ
• Shim JH
• Seo SJ

• KMID: 2368130
• DOI: http://doi.org/10.5021/ad.2016.28.6.765

Abstract

Eccrine syringofibroadenoma (ESFA) is a rare benign cutaneous adnexal lesion characterized by a hyperplastic epithelium and eccrine ductal differentiation. In the present case, a 73-year-old Korean male presented with symmetrical numerous widespread, pinkish nodules with a cobblestone appearance over both legs for 2 years. He had a history of generalized erythematous scaly patches over his entire body for 20 years. On histopathologic findings, diagnosis of ESFA was confirmed. Our unusual and interesting case emphasizes the first report described one case in which multiple cobblestone like ESFAs arising from long-standing exfoliative dermatitis.

Keyword

Eccrine syringofibroadenoma; Exfoliative dermatitis

MeSH Terms

Aged
Dermatitis, Exfoliative*
Diagnosis
Epithelium
Humans
Leg
Male

Figure

• 

  Fig. 1 (A, B) Clinical images of patient. Symmetrical numerous widespread, pinkish nodules with a cobblestone appearance over both legs.

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  Fig. 2 Histopathologically, acanthosis, hyperkeratosis with exfoliation and perivascular inflammatory infiltration are observed in the superficial dermis (H&E, ×100). (B) Reticular, thin anastomosing strands of uniform cuboidal epithelial cells indicated in the arrow are growing into the dermis with epithelial cords embedded in a fibrovascular stroma (H&E, ×200).

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