Investig Magn Reson Imaging.  2016 Dec;20(4):259-263. 10.13104/imri.2016.20.4.259.

Primary Diffuse Large B-Cell Lymphoma of the Seminal Vesicle: a Case Report

• Kwag KS
• Jang SK
• Yeon JW
• Kwon KW
• Son JH
• Kim HJ

• KMID: 2366409
• DOI: http://doi.org/10.13104/imri.2016.20.4.259

Abstract

Primary diffuse large B-cell lymphoma of the seminal vesicle is an extremely rare disorder, with only two cases reported in the English literature. Here, we present imaging findings of a case of primary diffuse large B-cell lymphoma of the seminal vesicle. On transrectal ultrasonography, the mass presented as a 3.0-cm-sized heterogeneous, hypoechoic lesion in the right seminal vesicle. Computed tomography (CT) revealed a mass with rim-like enhancement in the right seminal vesicle. On magnetic resonance imaging (MRI), the tumor showed iso-signal intensity on T1-weighted images and heterogeneously intermediate-high signal intensity on T2-weighted images. The tumor showed rim-like and progressive enhancement with non-enhancing portion on dynamic scanning. Diffusion restriction was observed in the mass. On fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging, a high standardized uptake value (maxSUV, 23.5) by the tumor was noted exclusively in the right seminal vesicle.

Keyword

Lymphoma; Seminal vesicles; Ultrasound; Multidetector computed tomography; Magnetic resonance imaging; Positron-emission tomography

MeSH Terms

B-Lymphocytes*
Diffusion
Electrons
Lymphoma
Lymphoma, B-Cell*
Magnetic Resonance Imaging
Multidetector Computed Tomography
Positron-Emission Tomography
Seminal Vesicles*
Ultrasonography

Figure

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  Fig. 1 Primary diffuse large B-cell lymphoma in the seminal vesicle in a 58-year-old man. Transrectal ultrasonography (TRUS) demonstrating a heterogeneous, hypoechoic mass (arrow) in the right seminal vesicle (a). CT images showing a mass with rim-like enhancement (arrows) in the right seminal vesicle on portal venous phase (b, c).

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  Fig. 2 Primary diffuse large B-cell lymphoma of the seminal vesicle in a 58-year-old man. T2-weighted axial MR image demonstrating a mass with subtle high signal intensity (arrow) in the right seminal vesicle (a); T1-weighted axial image demonstrating a mass of low signal intensity (b, arrow) ; diffusion-weighted imaging showing high intensity (arrow) with a high b-value (1000 s/mm2) (c). The tumor showed rim-like enhancement on 3-min delayed phase image (d, arrow) and progressive with a non-enhancing portion on 5-min delayed phase image (e, arrow). FDG PET/CT revealed a high standardized uptake value (maxSUV, 23.5) in the right seminal vesicle, suggesting a hypermetabolic mass (f, arrow).

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  Fig. 3 Primary diffuse large B-cell lymphoma of the seminal vesicle in a 58-year-old man. Staining of the biopsy from the seminal vesicle mass showing diffuse proliferation of large neoplastic lymphoid cells (a: × 200, H&E staining). Immunohistochemical staining showing neoplastic cells expressing CD79a, confirming their B-cell lineage (b: × 400).

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