Yonsei Med J.  2015 Jul;56(4):895-903. 10.3349/ymj.2015.56.4.895.

Changes in the Practice of Coronary Revascularization between 2006 and 2010 in the Republic of Korea

Affiliations
  • 1Health Technology Assessment Team, Health Insurance Review and Assessment Service, Seoul, Korea.
  • 2Division of Cardiology, Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
  • 3Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea. preman@yuhs.ac
  • 4National Cancer Center, Goyang, Korea.

Abstract

PURPOSE
Evidence suggests that technological innovations and reimbursement schemes of the National Health Insurance Service may have impacted the management of coronary artery disease. Thus, we investigated changes in the practice patterns of coronary revascularization.
MATERIALS AND METHODS
Revascularization and in-hospital mortality among Koreans > or =20 years old were identified from medical claims filed between 2006 and 2010. The age- and sex-standardized procedure rate per 100000 person-years was calculated directly from the distribution of the 2008 Korean population.
RESULTS
The coronary revascularization rate increased from 116.1 (95% confidence interval, 114.9-117.2) in 2006 to 131.0 (129.9-132.1) in 2010. Compared to the rate ratios in 2006, the rate ratios for percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery in 2010 were 1.16 (1.15-1.17) and 0.80 (0.76-0.84), respectively. Among patients who received PCI, the percentage with drug-eluting stents increased from 89.1% in 2006 to 93.0% in 2010. In-hospital mortality rates from PCI significantly increased during the study period (p=0.03), whereas those from CABG significantly decreased (p=0.01). The in-hospital mortality rates for PCI and CABG were higher in elderly and female patients and at the lowest-volume hospitals.
CONCLUSION
The annual volume of coronary revascularization continuously increased between 2006 and 2010 in Korea, although this trend differed according to procedure type. A high percentage of drug-eluting stent procedures and a high rate of in-hospital mortality at low-volume hospitals were noted.

Keyword

Myocardial revascularization; percutaneous coronary intervention; insurance; reimbursement

MeSH Terms

Adult
Aged
Aged, 80 and over
Coronary Artery Bypass/*statistics & numerical data/trends
Coronary Artery Disease/*surgery
Drug-Eluting Stents
Female
Hospital Mortality
Humans
Male
Middle Aged
Myocardial Revascularization/*methods/*trends
Percutaneous Coronary Intervention/*statistics & numerical data/trends
Republic of Korea/epidemiology

Figure

  • Fig. 1 Quarterly distribution of the number of percutaneous coronary intervention (PCI) procedures according to the type of procedure from 2006 to 2010 in the Republic of Korea. BMS, bare-metal stent; DES-1G, first-generation drug-eluting stent; DES-2G, second-generation drug-eluting stent; DES-3G, third-generation drug-eluting stent.


Cited by  6 articles

Descriptive Study on the Korean Status of Percutaneous Coronary Intervention Using National Health Insurance Service-National Sample Cohort (NHIS-NSC) Database: Focused on Temporal Trend
Jidong Sung, Kyung Pyo Hong
Korean Circ J. 2019;49(12):1155-1163.    doi: 10.4070/kcj.2019.0080.

Percutaneous Coronary Intervention Is More Beneficial Than Optimal Medical Therapy in Elderly Patients with Angina Pectoris
Hoyoun Won, Ae-Young Her, Byeong-Keuk Kim, Yong Hoon Kim, Dong-Ho Shin, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Hyuck Moon Kwon, Yangsoo Jang, Myeong-Ki Hong
Yonsei Med J. 2016;57(2):382-387.    doi: 10.3349/ymj.2016.57.2.382.

Nobori-Biolimus-Eluting Stents versus Resolute Zotarolimus-Eluting Stents in Patients Undergoing Coronary Intervention: A Propensity Score Matching
Ayman Tantawy, Chul-Min Ahn, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Meong-Ki Hong
Yonsei Med J. 2017;58(2):290-295.    doi: 10.3349/ymj.2017.58.2.290.

The Effect of Sex and Anthropometry on Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention for Complex Coronary Lesions
Seung-Yul Lee, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
Yonsei Med J. 2017;58(2):296-304.    doi: 10.3349/ymj.2017.58.2.296.

Comparison of Clinical Outcomes between the Right and Left Radial Artery Approaches from the Korean Transradial Coronary Intervention Registry
Ji Young Park, Seung-Woon Rha, Byong Geol Choi, Dong Ju Oh, Cheol Ung Choi, Young-Jin Youn, Junghan Yoon
Yonsei Med J. 2017;58(3):521-526.    doi: 10.3349/ymj.2017.58.3.521.

Routine Angiographic Follow-Up versus Clinical Follow-Up after Percutaneous Coronary Intervention in Acute Myocardial Infarction
Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Byoung Geol Choi, Minsuk Shim, Se Yeon Choi, Jae Kyeong Byun, Hu Li, Woohyeun Kim, Jun Hyuk Kang, Jah Yeon Choi, Eun Jin Park, Sung Hun Park, Sunki Lee, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh
Yonsei Med J. 2017;58(4):720-730.    doi: 10.3349/ymj.2017.58.4.720.


Reference

1. Feldman DN, Gade CL, Slotwiner AJ, Parikh M, Bergman G, Wong SC, et al. Comparison of outcomes of percutaneous coronary interventions in patients of three age groups (<60, 60 to 80, and >80 years) (from the New York State Angioplasty Registry). Am J Cardiol. 2006; 98:1334–1339.
Article
2. Huang HW, Brent BN, Shaw RE. Trends in percutaneous versus surgical revascularization of unprotected left main coronary stenosis in the drug-eluting stent era: a report from the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR). Catheter Cardiovasc Interv. 2006; 68:867–872.
Article
3. Kappetein AP, Dawkins KD, Mohr FW, Morice MC, Mack MJ, Russell ME, et al. Current percutaneous coronary intervention and coronary artery bypass grafting practices for three-vessel and left main coronary artery disease. Insights from the SYNTAX run-in phase. Eur J Cardiothorac Surg. 2006; 29:486–491.
Article
4. van Domburg RT, Lemos PA, Takkenberg JJ, Liu TK, van Herwerden LA, Arampatzis CA, et al. The impact of the introduction of drug-eluting stents on the clinical practice of surgical and percutaneous treatment of coronary artery disease. Eur Heart J. 2005; 26:675–681.
Article
5. Morice MC, Serruys PW, Kappetein AP, Feldman TE, Ståhle E, Colombo A, et al. Outcomes in patients with de novo left main disease treated with either percutaneous coronary intervention using paclitaxel-eluting stents or coronary artery bypass graft treatment in the Synergy Between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery (SYNTAX) trial. Circulation. 2010; 121:2645–2653.
Article
6. Rodés-Cabau J, Deblois J, Bertrand OF, Mohammadi S, Courtis J, Larose E, et al. Nonrandomized comparison of coronary artery bypass surgery and percutaneous coronary intervention for the treatment of unprotected left main coronary artery disease in octogenarians. Circulation. 2008; 118:2374–2381.
Article
7. Hlatky MA, Boothroyd DB, Bravata DM, Boersma E, Booth J, Brooks MM, et al. Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials. Lancet. 2009; 373:1190–1197.
Article
8. Legrand VM, Garg S, Serruys PW, Virtanen KS, Szurawitzki G, Voudris V, et al. Influence of age on the clinical outcomes of coronary revascularisation for the treatment of patients with multivessel de novo coronary artery lesions: sirolimus-eluting stent vs. coronary artery bypass surgery and bare metal stent, insight from the multicentre randomised Arterial Revascularisation Therapy Study Part I (ARTS-I) and Part II (ARTS-II). EuroIntervention. 2011; 6:838–845.
Article
9. Schapiro-Dufour E, Cucherat M, Velzenberger E, Galmiche H, Denis C, Machecourt J. Drug-eluting stents in patients at high risk of restenosis: assessment for France. Int J Technol Assess Health Care. 2011; 27:108–117.
Article
10. Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schömig A, et al. Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis. Lancet. 2007; 370:937–948.
Article
11. Jones WS, Patel MR, Holleran SA, Harrison JK, O'Connor CM, Phillips HR 3rd. Trends in the use of diagnostic coronary angiography, percutaneous coronary intervention, and coronary artery bypass graft surgery across North Carolina. Am Heart J. 2011; 162:932–937.
Article
12. Douglas PS, Brennan JM, Anstrom KJ, Sedrakyan A, Eisenstein EL, Haque G, et al. Clinical effectiveness of coronary stents in elderly persons: results from 262,700 Medicare patients in the American College of Cardiology-National Cardiovascular Data Registry. J Am Coll Cardiol. 2009; 53:1629–1641.
13. Boden WE, O'Rourke RA, Teo KK, Hartigan PM, Maron DJ, Kostuk WJ, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007; 356:1503–1516.
Article
14. Daemen J, Wenaweser P, Tsuchida K, Abrecht L, Vaina S, Morger C, et al. Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. Lancet. 2007; 369:667–678.
Article
15. Shuchman M. Trading restenosis for thrombosis? New questions about drug-eluting stents. N Engl J Med. 2006; 355:1949–1952.
Article
16. Epstein AJ, Polsky D, Yang F, Yang L, Groeneveld PW. Coronary revascularization trends in the United States, 2001-2008. JAMA. 2011; 305:1769–1776.
Article
17. Puricel S, Oberhänsli M, Guntern P, Lehmann S, Goy JJ, Arroyo D, et al. Long-term comparison of everolimus-eluting and biolimus-eluting stents. EuroIntervention. 2013; 9:336–344.
Article
18. Gerber Y, Rihal CS, Sundt TM 3rd, Killian JM, Weston SA, Therneau TM, et al. Coronary revascularization in the community. A population-based study, 1990 to 2004. J Am Coll Cardiol. 2007; 50:1223–1229.
19. Hassan A, Newman A, Ko DT, Rinfret S, Hirsch G, Ghali WA, et al. Increasing rates of angioplasty versus bypass surgery in Canada, 1994-2005. Am Heart J. 2010; 160:958–965.
Article
20. Nallamothu BK, Young J, Gurm HS, Pickens G, Safavi K. Recent trends in hospital utilization for acute myocardial infarction and coronary revascularization in the United States. Am J Cardiol. 2007; 99:749–753.
Article
21. Riley RF, Don CW, Powell W, Maynard C, Dean LS. Trends in coronary revascularization in the United States from 2001 to 2009: recent declines in percutaneous coronary intervention volumes. Circ Cardiovasc Qual Outcomes. 2011; 4:193–197.
Article
22. Neyt M, Van Brabandt H, Devriese S, De Laet C. Cost-effectiveness analyses of drug eluting stents versus bare metal stents: a systematic review of the literature. Health Policy. 2009; 91:107–120.
Article
23. Applegate RJ, Sacrinty MT, Kutcher MA, Baki TT, Gandhi SK, Santos RM, et al. Comparison of drug-eluting versus bare metal stents on later frequency of acute myocardial infarction and death. Am J Cardiol. 2007; 99:333–338.
Article
24. Ryan J, Linde-Zwirble W, Engelhart L, Cooper L, Cohen DJ. Temporal changes in coronary revascularization procedures, outcomes, and costs in the bare-metal stent and drug-eluting stent eras: results from the US Medicare program. Circulation. 2009; 119:952–961.
Article
25. Hannan EL, Wu C, Walford G, Culliford AT, Gold JP, Smith CR, et al. Drug-eluting stents vs. coronary-artery bypass grafting in multivessel coronary disease. N Engl J Med. 2008; 358:331–341.
Article
26. Malenka DJ, Wennberg DE, Quinton HA, O'Rourke DJ, McGrath PD, Shubrooks SJ, et al. Gender-related changes in the practice and outcomes of percutaneous coronary interventions in Northern New England from 1994 to 1999. J Am Coll Cardiol. 2002; 40:2092–2101.
Article
27. Jollis JG, Peterson ED, DeLong ER, Mark DB, Collins SR, Muhlbaier LH, et al. The relation between the volume of coronary angioplasty procedures at hospitals treating Medicare beneficiaries and short-term mortality. N Engl J Med. 1994; 331:1625–1629.
Article
28. Rosenthal GE, Vaughan Sarrazin M, Hannan EL. In-hospital mortality following coronary artery bypass graft surgery in Veterans Health Administration and private sector hospitals. Med Care. 2003; 41:522–535.
Article
29. McGrath PD, Wennberg DE, Dickens JD Jr, Siewers AE, Lucas FL, Malenka DJ, et al. Relation between operator and hospital volume and outcomes following percutaneous coronary interventions in the era of the coronary stent. JAMA. 2000; 284:3139–3144.
Article
30. Lee HA, Park H. Trends in ischemic heart disease mortality in Korea, 1985-2009: an age-period-cohort analysis. J Prev Med Public Health. 2012; 45:323–328.
Article
31. Lee S, Baek K, Chun K. Cost-effectiveness of drug-eluting vs. bare-metal stents in patients with coronary artery disease from the Korean National Health Insurance Database. Yonsei Med J. 2014; 55:1533–1541.
Article
32. Lichtman JH, Wang Y, Jones SB, Leifheit-Limson EC, Shaw LJ, Vaccarino V, et al. Age and sex differences in inhospital complication rates and mortality after percutaneous coronary intervention procedures: evidence from the NCDR(®). Am Heart J. 2014; 167:376–383.
Article
33. Shaw RE, Anderson HV, Brindis RG, Krone RJ, Klein LW, McKay CR, et al. Development of a risk adjustment mortality model using the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR) experience: 1998-2000. J Am Coll Cardiol. 2002; 39:1104–1112.
Article
Full Text Links
  • YMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr