Int Neurourol J.  2016 Sep;20(3):232-239. 10.5213/inj.1632508.254.

Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients

• Tanik N
• Tanik S
• Albayrak S
• Zengin K
• Inan LE
• Caglayan E
• Celikbilek A
• Kirboga K
• Gurdal M

• KMID: 2365717
• DOI: http://doi.org/10.5213/inj.1632508.254

Abstract

PURPOSE
Diabetes mellitus (DM) is a chronic metabolic disorder that often leads to complications. We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests.
METHODS
We included 80 female and 40 male type 2 diabetic patients in this prospective study. Diabetic polyneuropathy evaluations were conducted using the Douleur Neuropathique 4 Questions (DN4), and overactive bladder (OAB) evaluations were performed using the Overactive Bladder Questionnaire (OAB-V8). The patients were also evaluated for retinopathy and nephropathy. The diabetic male and female patients with or without OAB were chosen and compared for microvascular complications (polyneuropathy, retinopathy, and nephropathy).
RESULTS
There were no significant correlations between OAB and retinopathy as well as between OAB and nephropathy among diabetic patients (female patients, P>0.05; male patients, P>0.05). However, the patients with OAB were significantly more likely to develop polyneuropathy (female patients, P<0.05; male patients, P<0.05).
CONCLUSIONS
In diabetic patients, OAB and diabetic peripheral neuropathy are significantly correlated. These correlations were demonstrated using short, understandable, valid, and reliable disease-specific tests without invasive measures. Using these screening tests, both neurologists and urologists can easily diagnose these complications.

Keyword

Diabetic Neuropathies; Urinary Bladder, Overactive; Screening Tests

MeSH Terms

Diabetes Mellitus
Diabetic Neuropathies
Female
Humans
Male
Mass Screening
Peripheral Nervous System Diseases
Polyneuropathies*
Prospective Studies
Urinary Bladder
Urinary Bladder, Overactive*