Allergy Asthma Immunol Res.  2015 Mar;7(2):101-105. 10.4168/aair.2015.7.2.101.

Natural History and Risk Factors of Atopic Dermatitis in Children

Affiliations
  • 1Pediatric Allergy and Respiratory Center, Department of Pediatrics, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. bypyun@schmc.ac.kr

Abstract

Atopic dermatitis (AD) is one of the most common inflammatory allergic diseases with pruritic skin lesions particularly in infancy. It is considered to be the first step of atopic march and has variable disease courses. Many children with AD may resolve their AD symptoms with increasing age and may develop respiratory allergies such as asthma and rhinoconjunctivitis at certain ages. Natural course of AD has been supported by many cross-sectional and longitudinal studies in many countries. In general, atopic dermatitis tends to be more severe and persistent in young children, particularly if they have some risk factors including genetic factors. It appears that approximately 40%-70% of childhood AD will get resolved when they reach the age of 6-7 years. However, it is also observed that over half of the children with AD developed respiratory allergy during late childhood.

Keyword

Natural history; risk factor; children; atopic dermatitis

MeSH Terms

Asthma
Child*
Dermatitis, Atopic*
Humans
Hypersensitivity
Natural History*
Risk Factors*
Skin
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