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The Natural History of Peyronie’s Disease

Maida FD, Cito G, Lambertini L, Valastro F, Morelli G, Mari A, Carini M, Minervini A, Cocci A

Peyronie’s disease (PD), a fibrotic disorder of the tunica albuginea fully described in 1793 by French physician Francois de la Peyronie, is characterized by pain, plaque formation, penile deformity, and...
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Temporal trend in the natural history of ulcerative colitis in a country with a low incidence of ulcerative colitis from 2000 through 2018

Aniwan S, Limsrivilai J, Pongprasobchai S, Pausawasdi N, Prueksapanich P, Kongtub N, Rerknimitr R

Background/Aims: The incidence of ulcerative colitis (UC) in Thailand (crude incidence rate of 0.28 per 100,000 persons) is much lower than in the West. The burden of UC varies in...
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Increased Wall Enhancement Extent Representing Higher Rupture Risk of Unruptured Intracranial Aneurysms

Jiang Y, Xu F, Huang L, Lu G, Ge L, Wan H, Geng D, Zhang X

Objective : This study aims to investigate the relationship between aneurysm wall enhancement and clinical rupture risks based on the magnetic resonance vessel wall imaging (MR-VWI) quantitative methods. Methods : One...
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Recent Epidemiology of Nonalcoholic Fatty Liver Disease

Murag S, Ahmed A, Kim D

The ongoing obesity epidemic and the increasing recognition of metabolic syndrome have contributed to the growing prevalence of nonalcoholic fatty liver disease (NAFLD), the most common form of liver disease...
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Impact of Puberty in Pediatric Migraine: A Pilot Prospective Study

Fonseca E, Torres-Ferrús M, Gallardo VJ, Macaya A, Pozo-Rosich P

Background and Purpose: The short-term evolution of pediatric migraine remains unclear. We aimed to describe the evolution of migraine before and after puberty and its relationship with lifestyle habits. Methods: We...
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Management of incidentally found unruptured intracranial aneurysms

Cho WS, Lee SH, Kang HS, Kim JE

Incidentally found unruptured intracranial aneurysms are increasing because of the popularity of medical checkups with cerebrovascular imaging and the recent growing interest in health. Accordingly, surgical or endovascular treatments are...
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Natural History of Untreated Early Gastric Cancer

Ha TS

Early gastric cancer (EGC), which is defined as a lesion confined to the mucosa or the submucosal layer, regardless of metastasis to the lymph node, has a good prognosis than...
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Growth Pattern and Prognostic Factors of Untreated Nonfunctioning Pituitary Adenomas

Hwang K, Kwon T, Park J, Joo JD, Han JH, Oh CW, Kim CY

OBJECTIVE: Pituitary adenomas (PAs) are often detected as incidental findings. However, the natural history remains unclear. The objective of this study was to evaluate the natural history and growth pattern...
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Natural History and Treatment Indications of Chronic Hepatitis B

Sinn DH

HBV is the most common etiology of both liver cirrhosis and hepatocellular carcinoma in Korea. Despite much progress made, the currently available antiviral therapies cannot eradicate or eliminate this virus....
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Characteristics and Clinical Course of Fusiform Middle Cerebral Artery Aneurysms According to Location, Size, and Configuration

Seo D, Lee SU, Oh CW, Kwon OK, Ban SP, Kim T, Byoun HS, Kim YD, Lee Y, Won YD, Bang JS

OBJECTIVE: To analyze the angiographic features and clinical course, including treatment outcomes and the natural course, of fusiform middle cerebral artery aneurysms (FMCAAs) according to their location, size, and configuration. METHODS:...
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The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion

Choi SI, Park JC

The concept and pathological diagnostic criteria of gastric adenoma (dysplasia) differ between Western countries and Japan, and discrepancies between histopathological examinations before and after endoscopic resection may occur. Therefore, the...
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Clinical manifestations of Rathke’s cleft cysts and their natural progression during 2 years in children and adolescents

Jung JE, Jin J, Jung MK, Kwon A, Chae HW, Kim DH, Kim HS

PURPOSE: Rathke’s cleft cyst (RCC) is an asymptomatic benign lesion. With increased interest in pediatric endocrinology, the prevalence of RCCs in children is also increasing. However, the clinical relevance and...
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Can men with prostates sized 80 mL or larger be managed conservatively?

Lee A, Lee HJ, Foo KT

PURPOSE: To analyze the long-term clinical outcomes of men with large prostate sizes of 80 mL and greater who were managed conservatively. MATERIALS AND METHODS: We retrospectively analyzed men with prostate...
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Clinical Features, Natural History, and Complications of Chronic Pancreatitis

Choo JW, Moon SH

Chronic pancreatitis is a debilitating disease characterized by abdominal pain, exocrine insufficiency, and diabetes mellitus and has had great social, economic, and psychological impacts. Traditional definition of chronic pancreatitis has...
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Natural Short-term Course of Recurrent Macular Edema Following Intravitreal Bevacizumab Therapy in Branch Retinal Vein Occlusion

Yoo SJ, Kim JH, Lee TG, Kim JW, Cho SW, Han JI

PURPOSE: To evaluate the 3-month natural course of recurrent macular edema secondary to branch retinal vein occlusion (BRVO) treated with intravitreal bevacizumab. METHODS: This retrospective, observational study included 36 eyes with...
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Natural History of Lumbar Degenerative Kyphosis with Conservative Treatment

Kim WJ, Chang SH, Lee GS, Kim YH, Park KY, Park KH, Choy WS

STUDY DESIGN: Retrospective study. OBJECTIVES: To evaluate the natural history of conservatively treated lumbar degenerative kyphosis (LDK). SUMMARY OF LITERATURE REVIEW: The correlations between the clinical and radiologic parameters of general adult...
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Natural History of Early Gastric Cancer: a Case Report and Literature Review

Iwai T, Yoshida M, Ono H, Kakushima , Takizawa K, Tanaka M, Kawata N, Ito S, Imai K, Hotta K, Ishiwatari H, Matsubayashi H

Early detection and treatment decrease the mortality rate associated with gastric cancer (GC). However, the natural history of GC remains unclear. An 85-year-old woman was referred to our hospital for...
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Is Routine Thromboprophylaxis Needed in Korean Patients Undergoing Unicompartmental Knee Arthroplasty?

Koh IJ, Kim JH, Kim MS, Jang SW, Kim C, In Y

This study was undertaken to determine the prevalence and the natural course of venous thromboembolism (VTE) without thromboprophylaxis to ascertain whether routine thromboprophylaxis is necessary following unicompartmental knee arthroplasty (UKA)...
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Analysis of Natural History of Upper Gastrointestinal Subepithelial Tumors and Factors Related to Tumor Growth Demonstrated by Endoscopic Ultrasonography

Han YJ, Kim SE, Park MI, Park SJ, Moon W, Kim JH, Seo KI, Kim HJ, Jung JK

BACKGROUND/AIMS: Small subepithelial tumors (SETs) are often found incidentally during esophagoduodenoscopy, and EUS is a useful tool for assessing SETs. This study aimed to evaluate the natural history of SETs...
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Postoperative biological and clinical outcomes following uncomplicated pancreaticoduodenectomy

Lermite E, Wu T, Sauvanet A, Mariette C, Paye F, Muscari F, Cunha AS, Sastre B, Arnaud JP, Pessaux P, Federation de Recherche en Chirurgie

BACKGROUNDS/AIMS: The aim of this study was to describe clinical and biological changes in a group of patients who underwent pancreaticoduodenectomy (PD) without any complication during the postoperative period. These...
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