Arch Craniofac Surg.  2016 Dec;17(4):237-239. 10.7181/acfs.2016.17.4.237.

The Effect of Botulinum Toxin on an Iatrogenic Sialo-Cutaneous Fistula

Affiliations
  • 1Department of Plastic and Reconstructive Surgery, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea. byps@icould.com

Abstract

A sialo-cutaneous fistula is a communication between the skin and a salivary gland or duct discharging saliva. Trauma and iatrogenic complications are the most common causes of this condition. Treatments include aspiration, compression, and the administration of systemic anticholinergics; however, their effects are transient and unsatisfactory in most cases. We had a case of a patient who developed an iatrogenic sialo-cutaneous fistula after wide excision of squamous cell carcinoma in the parotid region that was not treated with conventional management, but instead completely resolved with the injection of botulinum toxin. Based on our experience, we recommend the injection of botulinum toxin into the salivary glands, especially the parotid gland, as a conservative treatment option for sialo-cutaneous fistula.

Keyword

Salivary gland fistula; Botulinum toxins; Squamous cell carcinoma

MeSH Terms

Botulinum Toxins*
Carcinoma, Squamous Cell
Cholinergic Antagonists
Fistula*
Humans
Parotid Gland
Parotid Region
Saliva
Salivary Gland Fistula
Salivary Glands
Skin
Botulinum Toxins
Cholinergic Antagonists
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