Korean J Pediatr.  2016 Nov;59(Suppl 1):S72-S75. 10.3345/kjp.2016.59.11.S72.

Eosinophilic gastroenteritis in an 18-year-old male with prolonged nephrotic syndrome

• Choi DM
• Pyun JE
• Yim HE
• Yoo KH
• Shim JO
• Lee EJ
• Won NH

• KMID: 2362260
• DOI: http://doi.org/10.3345/kjp.2016.59.11.S72

Abstract

Eosinophilic gastroenteritis is a rare disease characterized by prominent eosinophilic tissue infiltration of the gastrointestinal tract. Here, we report a case of eosinophilic gastroenteritis in an 18-year-old patient with prolonged nephrotic syndrome who presented with abdominal pain and peripheral hypereosinophilia. During the previous 2 years, he had visited local Emergency Department several times because of epigastric pain and nausea. He had been treated with steroid-dependent nephrotic syndrome since 3 years of age. Tests ruled out allergic and parasitic disease etiologies. Gastroduodenoscopy with biopsy revealed marked eosinophilic infiltration in the duodenum. Renal biopsy findings indicated minimal change disease spectrum without eosinophilic infiltration. The oral deflazacort dosage was increased, and the patient was discharged after abdominal pain resolved. To our knowledge, this is the first report of eosinophilic gastroenteritis in a patient with minimal change disease.

Keyword

Nephrotic syndrome; Eosinophilic enteropathy; Eosinophilia

MeSH Terms

Abdominal Pain
Adolescent*
Biopsy
Duodenum
Emergency Service, Hospital
Eosinophilia
Eosinophils*
Gastroenteritis*
Gastrointestinal Tract
Humans
Male*
Nausea
Nephrosis, Lipoid
Nephrotic Syndrome*
Parasitic Diseases
Rare Diseases