Ann Dermatol.  1991 Jul;3(2):133-137. 10.5021/ad.1991.3.2.133.

A Case of Cytophagic Histiocytic Panniculitis

• Lee DW
• Park BC
• Houh D
• Kim SY
• Kim HO
• Kim CW

• KMID: 2362006
• DOI: http://doi.org/10.5021/ad.1991.3.2.133

Abstract

Cytophagic histiocytic panniculitis(CHP) is a histiocytic disorder that was first described by Winkelmann and Crotty in 1980. We have recently experienced a case of CHP is a 21-year-old female who had developed recurrent fever and erythematous tender subcutaneous nodules, progressing to liver dysfunction and hemorrhagic diathesis. Histopathologically, infiltrates of large cytophagic histiocytes lacking atypia were present in the subcutis. Hemophagocytic histiocytes were observed in the bone marrow. Immunohistochemical studies were performed, and revealed positive immunoreactivity for lysozyme and T cell marker in the subcutaneous inflammatory lesions.

Keyword

Bean bag cell; Cytophagic histiocytic panniculitis

MeSH Terms

Bone Marrow
Female
Fever
Hemorrhagic Disorders
Histiocytes
Humans
Liver Diseases
Muramidase
Panniculitis*
Young Adult
Muramidase