Ann Dermatol.  1993 Jul;5(2):117-120. 10.5021/ad.1993.5.2.117.

Thalidomide Therapy on A Case of Prurigo Nodularis

• Baik YG
• Yu HJ
• Son SJ

• KMID: 2361704
• DOI: http://doi.org/10.5021/ad.1993.5.2.117

Abstract

Prurigo nodularis is a troublesome chronic dermatosis that showed unsatisfactory response to conventional therapies. Since thalidomide has been applied to the treatment of prurigo nodularis, although the action mechanism is still uncertain, many dermatologists have confirmed its effectiveness. We treated a 54-year-old male patient who had prurigo nodularis affecting the whole body for 10 years with 100 to 300mg of thalidomide daily as the sole therapy for 4 months. The skin lesions were flattened leaving postinflammatory hyperpigmentation and the pruritus also sub-sided. Two years after stopping thalidomide, no recurrence was observed.

Keyword

Prurigo nodularis; Thalidomide

MeSH Terms

Humans
Hyperpigmentation
Male
Middle Aged
Prurigo*
Pruritus
Recurrence
Skin
Skin Diseases
Thalidomide*
Thalidomide