J Dent Hyg Sci.  2016 Jun;16(3):235-241. 10.17135/jdhs.2016.16.3.235.

Effects of the Enamel Erosion Caused by Certain Antipyretic and Analgesic Medicines for Children

• Cheun SK
• Jeong MJ
• Ahn YS
• Lee YJ
• Ko MK
• Jeong SJ
• Lim DS

• KMID: 2360825
• DOI: http://doi.org/10.17135/jdhs.2016.16.3.235

Abstract

This study was conducted to provide basic understanding regarding possible enamel erosion by three kinds of fist-aid antipyretic and analgesic medicines over a period of time, with comparison and analysis of the resulting deciduous teeth surface and microhardness changes. The analysis was performed using energy dispersive X-ray spectroscopy (EDX) and scanning electron microscope (SEM) to examine the surface erosion and changes. The Kruskal-Wallis test show differences in surface erosion and changes after 3, 5 and 8 days of treatment as well as before and after the treatment in each group. According to the results, there was no significant difference in the early deciduous teeth enamel surface microhardness (p>0.01). However there were signigicant changes after 3, 5, and 8 days (p<0.01). Calcim (Ca) and phosphorous (P) analysis using EDX showed significant differences in the enamel characteristics according to each tissue area after 8 days (p<0.05), but there was no significant difference in any of the areas for P content (p>0.05). In the surface observation with the SEM treatment with Children's Tylenol® tablet, which has the lowest pH, looked the roughest, followed by Brufen syrup for children and Children's Tylenol® suspension. Based on these results, it should be considered that antipyretic and analgesic medicines for children, which have lower pH values, may cause tooth erosion. Hence, it is necessary to give special attention to oral hygiene in young children or infants by brushing their teeth after such drugs are administered.

Keyword

Antipyretics·analgesics; Deciduous tooth; Tooth erosion

MeSH Terms

Child*
Dental Enamel*
Humans
Hydrogen-Ion Concentration
Ibuprofen
Infant
Oral Hygiene
Spectrometry, X-Ray Emission
Tooth
Tooth Erosion
Tooth, Deciduous
Ibuprofen