Ann Dermatol.  1998 Apr;10(2):81-85. 10.5021/ad.1998.10.2.81.

Carcinosarcom a of the Skin: A New Combination of Squamous Cell Carcinoma and Chondrosarcoma

• Lee EK
• Yoon DH
• Kim TY
• Kim CW
• Lee HK
• Kang SJ

• KMID: 2359798
• DOI: http://doi.org/10.5021/ad.1998.10.2.81

Abstract

Carcinosarcoma is a rare malignant tumor composed of a mixture of neoplastic epithelial and mesenchymal elements, which has been reported in many organ systems, but its occurrence is very rare in the skin. An 81-year-old female patient presented with aml-year-history of a painful exophytic mass on the tip of the middle finger of the right hand involving the distal part of the nail bed. The mass was 1 × 1 × 0.6 cm in size, hard, flesh colored, ulcerated and easily bleeding. Microscopically, the epidermis at the margin of the tumor showed the characteristic findings of squamous cell carcinoma and the carcinomatous component was mixed with malignant mesenchymal components focally differentiating into chondrosarcoma. This combination of squamous cell carcinoma and chondrosarcoma has not been reported yet in the skin. She had a distal interphalanx amputation and no recurrence appeared for 1 year on follow-up.

Keyword

Carcinosarcoma; Chondrosarcoma; Skin; Squamous cell carcinoma

MeSH Terms

Aged, 80 and over
Amputation
Carcinoma, Squamous Cell*
Carcinosarcoma
Chondrosarcoma*
Epidermis
Epithelial Cells*
Female
Fingers
Follow-Up Studies
Hand
Hemorrhage
Humans
Recurrence
Skin*
Ulcer