A computed tomographic study of experimental pulmonalry infarction in rabbit

Choi, Y H; Kim, J H; Yun, K S; Kim, H J; Kang, H S; Kim, I O; Han, M C

Abstract

To evaluate the CT findings of pulmonary infarction, an experimental study was carried out using a total of 39 rabbits. Pulmonary embolization was performed with silk suture material and polyvinyl alcohol by trasfemoral catheterization. Sequential plain chest radiography and CT were performed during 5 week period after embolization. The rabbits were sacrificed and soft tissue radiography, CT and pathological examination of lung specimen fixed by inflation fixation technique were made. The results were as follows: 1. CT was more sensitive than plain chestradiography in detecting pulmonary infarction. 2. Characteristic CT finding was pleural based wedge shaped lesionwhich was noted in 57.1%, and the lesion without broad pleural base was noted in 7.1%. 3. The parenchymal lunglesion noted in CT was decreased in extent in 70.8% with complete resolution in only one case, and increased inextent in 29.2% with one total collapse of left lung. 4. Parenchymal lung lesions was detected in CT immediately after embolization (60%) and the incidence increased until 5 days(82.1%) and then decreased gradually. 5. Hounsfield number did not provide additonal significant information in diagnosis of pulmonary infarction. 6. CTproves to be an useful modality in the diagnosis of pulmonary infarction with sensitivity of 88%, specifictiy of80%, and diagnostic accuracy of 86.7%.

A computed tomographic study of experimental pulmonalry infarction in rabbit

Abstract

MeSH Terms

Cited

Save citations to file

Email citations