Korean J Anesthesiol.  1979 Dec;12(4):466-468.

Toxic Hepatitis following Halothane Anesthesia

• Im WM
• Lee CB

Abstract

A 17 year old girl underwent a surgery of spine fusion for a tuberculous cervical spine (C(4~5) ) under halothane-02 anesthesia. On the 1st postoperative day, sudden high fever(39.7 degrees C) with chillness and leukocytosis with eosinophilia were noted. On the following day, generalized jaundice, right hypochondralgia and slight hepatomegaly with marked impairment of liver function tests were noted. HB antigens were negative and there was no transfusion history of blood or blood products. About 2 months after operation, she was discharged with symptomatic improvement and almost normal laboratory data.

MeSH Terms

Anesthesia*
Drug-Induced Liver Injury*
Eosinophilia
Female
Halothane*
Hepatomegaly
Humans
Jaundice
Leukocytosis
Liver Function Tests
Spine
Halothane