J Korean Ophthalmol Soc.  2016 Oct;57(10):1549-1554. 10.3341/jkos.2016.57.10.1549.

Effects on Ocular Surface and Compliance of Orthokeratology Wear in Adults with Contact Lens Discomfort

• Kang MK
• Na KS
• Kim HS

• KMID: 2355409
• DOI: http://doi.org/10.3341/jkos.2016.57.10.1549

Abstract

PURPOSE
To evaluate the effects on the ocular surface and the compliance of overnight orthokeratology lenses wear in normal myopic adults experiencing contact lens discomfort.
METHODS
In this study, 28 eyes of 14 subjects were analyzed using overnight orthokeratology (OOK). This prospective study investigated the compliance of OOK wear using questionnaires, spherical equivalents, keratometry, and central corneal thickness. Ocular surface disease index, tear osmolarity, Schirmer's test I, tear film break-up time, and ocular surface staining score were evaluated as ocular surface parameters. Meibomian gland function was evaluated by assessing lid margin abnormality and meiboscore using noncontact meibography. The tests were performed before and 1 and 6 weeks after OOK wear.
RESULTS
The mean age of the subjects was 26.67 ± 3.26 years, and the average duration of previous contact lens use was 2.64 ± 2.41 years. The questionnaire results showed that OOK lenses were more comfortable to wear than conventional lenses. Significant changes in spherical equivalents, keratometry, and central corneal thickness were observed at 6 weeks compared with baseline values (all p < 0.001). No significant changes were detected in ocular surface or meibomian gland status at 1 and 6 weeks compared with baseline values (all p >0.05).
CONCLUSIONS
Based on the findings, OOK is a relatively safe modality with good compliance for normal myopic adults experiencing contact lens discomfort.

Keyword

Contact lens discomfort; Meibomian glands; Ocular surface; Overnight orthokeratology

MeSH Terms

Adult*
Compliance*
Humans
Meibomian Glands
Osmolar Concentration
Prospective Studies
Tears

Reference

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