J Dent Anesth Pain Med.  2016 Sep;16(3):209-212. 10.17245/jdapm.2016.16.3.209.

Dental anesthesia for patients with allergic reactions to lidocaine: two case reports

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea.
  • 2Department of Dental Anesthesiology, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea. stone90@snu.ac.kr

Abstract

Lidocaine, a local anesthetic commonly used in dental treatments, is capable of causing allergies or adverse effects similar to allergic reactions. However, the frequency of such occurrences in actual clinical settings is very rare, and even clinical tests on patients with known allergies to local anesthetics may often show negative results. When adverse effects, such as allergy to lidocaine, are involved, patients can be treated by testing other local anesthetics and choosing a local anesthetic without any adverse effects, or by performing dental treatment under general anesthesia in cases in which no local anesthetic without adverse effects is available. Along with a literature review, the authors of the present study report on two cases of patients who tested positive on allergy skin tests for lidocaine and bupivacaine and subsequently underwent successful dental treatments with either general anesthesia or a different local anesthetic.

Keyword

Allergy; Bupivacaine; Dental local anesthesia; Lidocaine

MeSH Terms

Anesthesia, Dental*
Anesthesia, General
Anesthetics, Local
Bupivacaine
Humans
Hypersensitivity*
Lidocaine*
Skin Tests
Anesthetics, Local
Bupivacaine
Lidocaine

Figure

  • Fig. 1 Skin prick test – positive skin reaction to lidocaine.


Reference

1. Batinac T, Sotosek Tokmadzic V, Peharda V, Brajac I. Adverse reactions and alleged allergy to local anesthetics: Analysis of 331 patients. J Dermatol. 2013; 40:522–527.
Article
2. Finder RL, Moore PA. Adverse drug reactions to local anesthesia. Dent Clin North Am. 2002; 46:747–757.
Article
3. Speca SJ, Boynes SG, Cuddy MA. Allergic reactions to local anesthetic formulations. Dent Clin North Am. 2010; 54:655–664.
Article
4. Fisher MM, Bowey CJ. Alleged allergy to local anaesthetics. Anaesth Intensive Care. 1997; 25:611–614.
Article
5. Ping B, Kiattavorncharoen S, Durward C, Im P, Saengsirinavin C, Wongsirichat N. Hemodynamic changes associated with a novel concentration of lidocaine hcl for impacted lower third molar surgery. J Dent Anesth Pain Med. 2015; 15:121–128.
Article
6. Noormalin A, Shahnaz M, Rosmilah M, Mujahid SH, Gendeh BS. Ige-mediated hypersensitivity reaction to lignocaine - a case report. Trop Biomed. 2005; 22:179–183.
7. González-Delgado P, Anton R, Soriano V, Zapater P, Niveiro E. Cross-reactivity among amide-type local anesthetics in a case of allergy to mepivacaine. J Investig Allergol Clin Immunol. 2006; 16:311–313.
8. Grzanka A, Wasilewska I, Sliwczynska M, Misiolek H. Hypersensitivity lo local anesthetics. Anaesthesiol Intensive Ther. 2016; 48:128–134.
9. Thyssen JP, Menne T, Elberling J, Plaschke P, Johansen JD. Hypersensitivity to local anaesthetics--update and proposal of evaluation algorithm. Contact Dermatitis. 2008; 59:69–78.
Article
10. Fellinger C, Wantke F, Hemmer W, Sesztak-Greinecker G, Wohrl S. The rare case of a probably true ige-mediated allergy to local anaesthetics. Case Rep Med. 2013; 2013:201586.
Article
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