Korean J Ophthalmol.  2016 Oct;30(5):392-393. 10.3341/kjo.2016.30.5.392.

Ocular Myasthenia Gravis in Monozygotic Twins with Mirror-image Myopic Anisometropia

Affiliations
  • 1Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea. mingming8@naver.com

Abstract

No abstract available.


MeSH Terms

Anisometropia*
Humans
Myasthenia Gravis*
Twins, Monozygotic*

Figure

  • Fig. 1 Fundus photographs showing the mirror-image myopic tilted disc, tigroid fundus, and reduction of foveal reflex in the left eye of twin 1 (A) and in the right eye of twin 2 (B), which is consistent with mirror-image amblyopia due to myopic anisometropia. Gaze photographs showing varied duction deficits at 19 years of age (C,D) and residual duction deficits 7 years later (E,F). (C) Twin 1 exhibited 55 prism diopters of left exotropia, and limited adduction in the left (-4) and right eye (-2). (D) Twin 2 exhibited ptosis of both eyes, limited adduction in the right eye (-4) and abduction in the left eye (-2). (E) Twin 1 is orthotropic in the primary position after muscle surgery; however, she still has an adduction deficit (-2) in the left eye. (F) Twin 2 exhibits 25 prism diopters of right exotropia, and markedly limited adduction (-4) in the right eye.


Reference

1. Hall JG. Twinning. Lancet. 2003; 362:735–743.
2. Okamoto F, Nonoyama T, Hommura S. Mirror image myopic anisometropia in two pairs of monozygotic twins. Ophthalmologica. 2001; 215:435–438.
3. Kim WK, Chung SA, Lee JB. Two cases of mirror-image eye anomalies in monozygotic twins. Korean J Ophthalmol. 2010; 24:314–317.
4. Vincent A, Palace J, Hilton-Jones D. Myasthenia gravis. Lancet. 2001; 357:2122–2128.
5. Punga AR, Nygren I, Askmark H, Stalberg EV. Monozygous twins with neuromuscular transmission defects at opposite sides of the motor endplate. Acta Neurol Scand. 2009; 119:207–211.
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