Pediatr Infect Vaccine.  2016 Aug;23(2):143-148. 10.14776/piv.2016.23.2.143.

A Case of Lemierre Syndrome Manifests with Persistent Fever and Neck Stiffness Following Acute Oropharyngeal Infection

• Lee Y
• Hong YS
• Kim SS

• KMID: 2353395
• DOI: http://doi.org/10.14776/piv.2016.23.2.143

Abstract

Lemierre syndrome is a rare disease involving multiple organs affected by septic emboli following oropharyngeal infection. After the introduction of penicillin in the 1940s, it became a "forgotten" disease. However, due to the development of diagnostic image modalities including neck computed tomography (CT) scan, the number of published reports of Lemierre syndrome and diagnosis has been increasing since the 1990s. In this report, we describe a case of Lemierre syndrome, following oropharyngeal infection in a 16-year-old patient, who manifested with persistent fever and neck stiffness. Neck ultrasonography confirmed thrombus formation in the right internal jugular vein without definite evidence of septic emboli to other organs. After the three-week-long antibiotics therapy was completed, the thrombus in the right internal jugular vein finally disappeared.

Keyword

Lemierre syndrome; Thrombophlebitis

MeSH Terms

Adolescent
Anti-Bacterial Agents
Diagnosis
Fever*
Humans
Jugular Veins
Lemierre Syndrome*
Neck*
Penicillins
Rare Diseases
Thrombophlebitis
Thrombosis
Ultrasonography
Anti-Bacterial Agents
Penicillins