Ann Dermatol.  2015 Jun;27(3):349-351. 10.5021/ad.2015.27.3.349.

Infantile Scabies Masquerading as Langerhans Cell Histiocytosis

• Yang YS
• Byun YS
• Kim JH
• Kim HO
• Park CW

• KMID: 2352518
• DOI: http://doi.org/10.5021/ad.2015.27.3.349

Abstract

No abstract available.

MeSH Terms

Histiocytosis, Langerhans-Cell*
Scabies*

Figure

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  Fig. 1 (A) The patient had several erythematous to brownish papules and nodules on her trunk on the initial visit. (B) Scales and erythematous patches on the palm of the patient after 1 month from the initial visit.

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  Fig. 2 (A) The dermal infiltration was composed of Langerhans cells admixed with lymphocytes and eosinophils (H&E stain, ×200). (B, C) Immunophenotyping demonstrated the majority of the histiocytic cells to be S-100 (B, ×40) and CD1a (C, ×100) positive. (D) Under dermoscopic magnification, a hangliderlike triangle indicating the scabies mites' head (arrow) was observed in the patient's palm.

Reference

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2. Hicks MI, Elston DM. Scabies. Dermatol Ther. 2009; 22:279–292.

3. Peterson CM, Eichenfield LF. Scabies. Pediatr Ann. 1996; 25:97–100.

4. Bhattacharjee P, Glusac EJ. Langerhans cell hyperplasia in scabies: a mimic of Langerhans cell histiocytosis. J Cutan Pathol. 2007; 34:716–720.

5. Favara BE, Jaffe R. The histopathology of Langerhans cell histiocytosis. Br J Cancer Suppl. 1994; 23:S17–S23.