Korean J Otorhinolaryngol-Head Neck Surg.
2016 Sep;59(9):688-691. 10.3342/kjorl-hns.2016.59.9.688.
A Case of Extramedullary Relapsed Acute Promyelocytic Leukemia Presenting as a Mass in the External Auditory Canal
- Affiliations
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- 1Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea. ljdent@schmc.ac.kr
- 2Department of ENT, Svay Chrum Referral Hospital, Cambodia.
- KMID: 2352358
- DOI: http://doi.org/10.3342/kjorl-hns.2016.59.9.688
Abstract
- Acute promyelocytic leukemia (APL) is a unique subtype of acute myelogenous leukemia for which complete remission is induced by using anticancer drugs with all-trans retinoic acid (ATRA). Extramedullary involvement at relapse is occasionally observed in patients with APL, and is said to be more common after treatment with ATRA. We describe a 35-year-old man who had a relapse due to a mass that developed in the external auditory canal after treatment with ATRA. He was successfully treated with arsenic trioxide and radiotherapy.
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