Korean J Otorhinolaryngol-Head Neck Surg.
2016 Sep;59(9):672-675. 10.3342/kjorl-hns.2016.59.9.672.
A Case of Histiocytic Sarcoma Arising in Head and Neck Region with Rhabdoid Differentiation
- Affiliations
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- 1Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Chungbuk National University, Cheongju, Korea. dwlee@chungbuk.ac.kr
- KMID: 2352354
- DOI: http://doi.org/10.3342/kjorl-hns.2016.59.9.672
Abstract
- Head and neck sarcomas account for about 1% of malignant head and neck tumors, and histiocytic sarcomas (HSs) account for less than 1% of all hematolymphoid neoplasms. These rare hematopoietic neoplasms are the result of a malignant proliferation of cells. They have morphological and immunophenotypic features of mature tissue histiocytes, which play a major role in processing and presenting antigens to T or B lymphocytes. The mesenchymal differentiation of HSs has not been reported. We describe a case of HS with rhabdoid differentiation in a 55-year-old man who presented with a 3×2.5×2 cm mass in the left supraclavicular area. To the best of our knowledge, this is the first report worldwide of a primary HS with rhabdoid differentiation.
