Yeungnam Univ J Med.  1994 Jun;11(1):63-71. 10.12701/yujm.1994.11.1.63.

Significance of Dexamethasone Suppression Test in Patients with Stroke

• Kim WN
• Kim SM
• Kee BS
• Park MY
• Hah JS
• Byun YJ

• KMID: 2352265
• DOI: http://doi.org/10.12701/yujm.1994.11.1.63

Abstract

The purpose of this study was to evaluate the effect of stroke on hypothalamic-pituitary axis using dexamethasone suppression test. The effects were evaluated according to age, sex, type, size, and lesion site of stroke. There tests were performed in 62 patients with stroke(cerebral infarction, 42 cases : intracerebral hemorrage, 20 cases) and 21 disabled controlled patients without intracranial diseases at Yeungnam University Hospital from June 1992 to June 1993. The results summarized as follows. 1. Cerebral infarction showed significantly higher frequency of DST non-suppression in stroke patients than control (p<0.05). 2. Patients with left hemisphere stroke showed more frequent abnormal neuroendocrine test results (p<0.01). 3. Patients with large infarction revealed strongly non-suppressed DST results(p<0.01). 4. Significantly higher basal cortisol level in patients with cerebral infarction was noted(p<0.01). 5. There are no statistical significance between DST results and sex, age, motor impairment, type of cerebral infarction.

MeSH Terms

Cerebral Infarction
Dexamethasone*
Humans
Hydrocortisone
Infarction
Stroke*
Dexamethasone
Hydrocortisone