Clin Mol Hepatol.  2015 Sep;21(3):212-219. 10.3350/cmh.2015.21.3.212.

Managing alcoholic liver disease

• Shah VH

• KMID: 2351020
• DOI: http://doi.org/10.3350/cmh.2015.21.3.212

Abstract

Alcoholic liver disease continues to be a significant cause of liver-related morbidity and mortality throughout the world. A number of diagnostic and prognostic models have been developed in the management of this condition, although specific roles for liver biopsy still remain particularly in the setting of alcoholic hepatitis. Despite a large number of recent treatment trials, the ideal pharmacotherapy approach remains undefined. Most essential is the supportive care and focus on abstinence and nutrition. Owing in part to a great deal of attention from governmental funding sources, a number of new treatment approaches are undergoing rigorous evaluation, hopefully providing future treatment options in this very severe condition.

Keyword

Liver transplantation; Alcoholic hepatitis; Corticosteroids; Alcohol

MeSH Terms

Adrenal Cortex Hormones/therapeutic use
Biomarkers/analysis
Humans
Interleukins/metabolism
Liver Diseases, Alcoholic/diagnosis/*therapy
Liver Transplantation
Pentoxifylline/therapeutic use
Prognosis
Adrenal Cortex Hormones
Biomarkers
Interleukins
Pentoxifylline