Korean J Dermatol.  2016 Feb;54(2):129-132.

A Case of Local and Generalized Skin Adverse Reactions after Pneumococcal Vaccination

• Kim HS
• Min J
• Hwang SH
• Lee HJ
• Jung HJ
• Nam JH
• Park JH
• Lee GY
• Kim WS

Abstract

Pneumococcus is the most frequently encountered causative pathogen in community-acquired pneumonia in elderly patients. The pneumococcal polysaccharide vaccine (PPV23) is widely used for preventing pneumococcal diseases in adults. PPV23 is relatively safe; however, some cutaneous adverse reactions, including localized mild inflammation associated with erythema, a sensation of heat, and tenderness, have been reported. Systemic reactions such as myalgia, arthralgia, and headache have also been reported, though severe adverse reactions are rare. In the Korean literature, a case of localized toxic reaction near the injection site after pneumococcal conjugate vaccine (PCV13) administration was previously reported. However, there are no published reports of a generalized skin rash after PPV23. Herein, we report a case of PPV23-induced generalized skin rash on the face, neck, upper trunk, and both arms with a local adverse reaction at the injection site after vaccination.

Keyword

Adverse reaction; Drug eruption; Maculopapular; Pneumococcal vaccines; Skin rash

MeSH Terms

Adult
Aged
Arm
Arthralgia
Drug Eruptions
Erythema
Exanthema
Headache
Hot Temperature
Humans
Inflammation
Myalgia
Neck
Pneumococcal Vaccines
Pneumonia
Sensation
Skin*
Streptococcus pneumoniae
Vaccination*
Pneumococcal Vaccines