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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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Updates of adult immunization in Korea

Shin HY, Yoo BW

An increase in the number of patients with infectious diseases in Korea, can be attributed to various factors, such as the prevalence of new infectious diseases of the 21st century,...
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Serotype Distribution and Antimicrobial Resistance of Invasive and Noninvasive Streptococcus pneumoniae Isolates in Korea between 2014 and 2016

Park DC, Kim SH, Yong D, Suh IB, Kim YR, Yi J, Song W, Song SA, Moon HW, Lee HK, Park KU, Kim S, Jeong SH, Lee J, Jeong J, Kim YK, Lee M, Cho J, Kim JW, Shin KS, Hwang SH, Chung JW, Woo HI, Lee CH, Ryoo N, Chang CL, Kim HS, Kim J, Shin JH, Kim SH, Lee MK, Lee SG, Jang SJ, Lee K, Suh H, Sohn YH, Kwon MJ, Lee HJ, Hong KH, Woo KS, Park CM, Shin JH

BACKGROUND: Several factors contribute to differences in Streptococcus pneumoniae serotype distribution. We investigated the serotype distribution and antimicrobial resistance of S. pneumoniae isolated between 2014 and 2016 in Korea. METHODS: We...
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Validation of a Multiplexed Opsonophagocytic Assay for 11 Additional Pneumococcal Serotypes and Its Application to Functional Antibody Evaluation Induced by Pneumococcal Polysaccharide Vaccine

Cha J, Kim HW, Lee JH, Lee S, Kim KH

BACKGROUND: Various pneumococcal vaccines have been evaluated for immunogenicity by opsonophagocytic assay (OPA). A multiplexed OPA (MOPA) for 13 pneumococcal serotypes was developed by Nahm and Burton, and expanded to...
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Surveillance and compensation claims for adverse events following immunization from 2011 to 2016 in the Republic of Korea

Kim MK, Lee YK, Kim TE, Kong I, Yang HJ, Suh ES

PURPOSE: In recent years, research on reported adverse events following immunization (AEFI) and claims filed for compensation has been lacking. We reviewed reported AEFIs and compensation claims in Korea from...
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Trend of Bacteria and Fungi Isolated from Cerebrospinal Fluid Culture in a Tertiary Care Hospital During Recent Two Decades (1997-2016)

Lee SG, Kim M, Hwang GY, Yoo G, Uh Y

BACKGROUND: Meningitis is a clinically important disease because of its high mortality and morbidity. The epidemiology of this disease has changed remarkably due to the introduction of pneumococcal vaccines and...
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Validation of the World Health Organization Enzyme-Linked Immunosorbent Assay for the Quantitation of Immunoglobulin G Serotype-Specific Anti-Pneumococcal Antibodies in Human Serum

Lee H, Lim SY, Kim KH

The World Health Organization (WHO) enzyme-linked immunosorbent assay (ELISA) guideline is currently accepted as the gold standard for the evaluation of immunoglobulin G (IgG) antibodies specific to pneumococcal capsular polysaccharide....
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Early Changes in the Serotype Distribution of Invasive Pneumococcal Isolates from Children after the Introduction of Extended-valent Pneumococcal Conjugate Vaccines in Korea, 2011-2013

Cho EY, Choi EH, Kang JH, Kim KH, Kim DS, Kim YJ, Ahn YM, Eun BW, Oh SH, Cha SH, Cho HK, Hong YJ, Kim KN, Kim NH, Kim YK, Kim JH, Lee H, Lee T, Kim HM, Lee KS, Kim CS, Park SE, Kim YM, Oh CE, Ma SH, Jo DS, Choi YY, Lee J, Bae GR, Park O, Park YJ, Kim ES, Lee HJ

This study was performed to measure early changes in the serotype distribution of pneumococci isolated from children with invasive disease during the 3-year period following the introduction of 10- and...
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Impact of IgM Antibodies on Cross-Protection against Pneumococcal Serogroups 6 and 19 after Immunization with 7-Valent Pneumococcal Conjugate Vaccine in Children

Cho HK, Park IH, Burton RL, Kim KH

Although it is well known that pneumococcal conjugate vaccines provide cross-protection against some vaccine-related serotypes, these mechanisms are still unclear. This study was performed to investigate the role of cross-protective...
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A Case of Local and Generalized Skin Adverse Reactions after Pneumococcal Vaccination

Kim HS, Min J, Hwang SH, Lee HJ, Jung HJ, Nam JH, Park JH, Lee GY, Kim WS

  • KMID: 2350792
  • Korean J Dermatol.
  • 2016 Feb;54(2):129-132.
Pneumococcus is the most frequently encountered causative pathogen in community-acquired pneumonia in elderly patients. The pneumococcal polysaccharide vaccine (PPV23) is widely used for preventing pneumococcal diseases in adults. PPV23 is...
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Indirect Effects of Pneumococcal Conjugate Vaccines in National Immunization Programs for Children on Adult Pneumococcal Disease

Kim YK, LaFon D, Nahm MH

The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have...
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Establishment and Application of a Multibead Serotyping Assay for Pneumococci in Korea

Kim HW, Lee S, Lee M, Kim KH

PURPOSE: Serotyping pneumococcal isolates is important to monitor efficacy of pneumococcal vaccines. Because of difficulties of typing pnueumocci, a multiplex bead-based (multibead) serotyping assay was recently introduced. The aim of...
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Pneumococcal disease and use of pneumococcal vaccines in Taiwan

Wei SH, Chiang CS, Chen CL, Chiu CH

The use of pneumococcal vaccine plays an important role for prevention of invasive pneumococcal disease (IPD). However, introducing the pneumococcal vaccine into the national immunization program (NIP) is complex and...
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Influenza and Pneumococcal Vaccine Coverage Rates among Patients Admitted to a Teaching Hospital in South Korea

Yang TU, Song JY, Noh JY, Cheong HJ, Kim WJ

BACKGROUND: Influenza and pneumococcal vaccinations can reduce morbidity and mortality especially in the elderly and patients with chronic medical disease. The purpose of this study was to estimate vaccination coverage...
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Phenotypic and Functional Analysis of HL-60 Cells Used in Opsonophagocytic-Killing Assay for Streptococcus pneumoniae

Kim KH, Seoh JY, Cho SJ

Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic...
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The Association between Asthma and Invasive Pneumococcal Disease: A Nationwide Study in Korea

Kwak BO, Choung JT, Park YM

The purpose of this study was to investigate the association between asthma and invasive pneumococcal disease (IPD) in Korea. A retrospective population-based cohort study was conducted using the Korean Health...
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Pneumococcal vaccine

Song JY, Cheong HJ

Streptococcus pneumoniae (pneumococcus) is an important pathogen with high morbidity and mortality worldwide. Pneumococcal vaccine is an important measure to reduce the pneumococcal disease burden. Currently, two pneumococcal vaccines are...
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Distribution of Serotypes and Antibiotic Susceptibility Patterns Among Invasive Pneumococcal Diseases in Saudi Arabia

A Al-Sherikh Y, K Gowda L, Mohammed Ali MM, John J, Khaled Homoud Mohammed D, Chikkabidare Shashidhar P

BACKGROUND: Streptococcus pneumoniae causes life-threatening infections such as meningitis, pneumonia, and febrile bacteremia, particularly in young children. The increasing number of drug-resistant isolates has highlighted the necessity for intervening and...
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Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines

Lee H, Choi EH, Lee HJ

The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of...
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Evaluation of Antibody Response to Polysaccharide Vaccine and Switched Memory B Cells in Pediatric Patients with Inflammatory Bowel Disease

Fallahi G, Aghamohammadi A, Khodadad A, Hashemi M, Mohammadinejad P, Asgarian-Omran H, Najafi M, Farhmand F, Motamed F, Soleimani , Soheili H, Parvaneh N, Darabi B, Nasiri Kalmarzi R, Pourhamdi , Abolhassani H, Mirminachi B, Rezaei N

  • KMID: 1774524
  • Gut Liver.
  • 2014 Jan;8(1):24-28.
BACKGROUND/AIMS: Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract, whose etiologies are still unknown. This study was performed to evaluate the humoral immune response in terms...
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