J Korean Assoc Oral Maxillofac Surg.  2016 Aug;42(4):187-192. 10.5125/jkaoms.2016.42.4.187.

The effects of high-fat diet on implant osseointegration: an experimental study

• Dündar S
• Yaman F
• Ozupek MF
• Saybak A
• Gul M
• Asutay F
• Kirtay M
• Ozercan IH

• KMID: 2350070
• DOI: http://doi.org/10.5125/jkaoms.2016.42.4.187

Abstract

OBJECTIVES
In this study, we investigated whether a high-fat diet (HFD) affected the bone implant connection (BIC) in peri-implant bone.
MATERIALS AND METHODS
Four male rabbits were used in this study. Dental implant surgery was introduced into each tibia, and four implants were integrated into each animal. In both the normal diet (ND) group (n=2) and HFD group (n=2), 8 implants were integrated, for a total of 16 integrated implants. The animals continued with their respective diets for 12 weeks post-surgery. Afterward, the rabbits were sacrificed, and the BIC was assessed histomorphometrically.
RESULTS
Histologic and histomorphometric analyses demonstrated that BIC was not impaired in the HFD group compared to the ND group.
CONCLUSION
Within the limitations of this study, we found that HFD did not decrease the BIC in rabbit tibias.

Keyword

Bone implant contact; Osseointegration; Titanium implants; High-fat diet; Histomorphometric analysis

MeSH Terms

Animals
Dental Implants
Diet
Diet, High-Fat*
Humans
Male
Osseointegration*
Rabbits
Tibia
Dental Implants

Figure

• 

  Fig. 1 A, B. Histologic view of the control group (A: ×2, B: ×4). C, D. Histologic view of the high-fat diet group (C: ×2, D: ×4).

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