Korean J Anesthesiol.  1984 Dec;17(4):288-294.

Change in Serum Potassium and Sodium following Succinylcholine Chloride Administration in Patients with Infection

• Chah SH
• Lee CH

Abstract

Transient hyperkalmia following intravenous administration of succinylcholine chloride is well known in normal patients. Increase in serum potassium(K+) can be greater in disease state, such as burn, massive trauma, uremia, neuromuscular disease, and tetanus. In the present study, changes in serum potassium and sodium level in 20 control group and 20 patients with infections of varying severity were measured after administration of SCC. The following results were obtained. 1) In all infected patients, serum potassium concentration was increased, hile wonly 70% of the control group was increased. 2) Serum potassium levels after administration of succinylcholine chloride increased in the control group(average 0.40+/-0.9mEq/L) and in the infected group(average 0.68+/-0.15 mEq/L). 3) The paek elevation of serum potassium level was 5 min. after administration of succinylcholine chloride in both groups. 4) There was asignificantly increased serum potassium concentration(p<0.01) in the infected group compared to the control group. 5) Serum K was increased above 0.5mEq/L in serum potassium level regardless of duration of infection. 6) Serum sodium concentration after administration of succinylcholine chloride was slightly decreased in both groups, but statistically this was not significant(p>0.05).

MeSH Terms

Administration, Intravenous
Burns
Humans
Neuromuscular Diseases
Potassium*
Sodium*
Succinylcholine*
Tetanus
Uremia
Potassium
Sodium
Succinylcholine