Korean J Anesthesiol.  1974 Jan;7(1):85-90.

Serum Potassium Change in Burned Patient Intravenous Suceinylcholine Iodide

• Yoo JS
• Chon SU

Abstract

Transient hyperkalemia is well known to occur in man following intravenous administration of succinylcholine chloride (Anectine). Furthermore, massive hyperkalemia following succinylcholine chloride administration is a recognized danger in patients with severe burns, massive trauma, muscle dystrophy, and peripheral nerve injury or lesions on central nervous system with skeletal muscle paralysis. Increased serum potassium may lead to severe cardiac arrhythmia or cardiac arrest. Reported mary literatures, this was shown for succinylcholine chloride but not for succinylcholine iodide. The authors studied succinylcholine iodide intravenous administration for burned patient as to whether serum potassium changes or not. Effects of intravenous succinylcholine iodide on serum potassium, ECG and fasciculation were studied in fifteen burned patients. For serum potassium change, venous blood sample was drawn at preoperative period and at 10 minutes after succinylcholine iodide administration. Results were as follows; 1. Serum potassium was increased at 10 minutes after succinylcholine administration (4.47+/-0.65 mEq/L) than the preoperative value (4.17+/-0.51 mEq/L). Mean increase was 0.30 mEq/L. 2. In ECG change, only one patient showed transient premature ventricular contraction during induction of anesthesia. In this case serum potassium was increased 0.8 mEq/L (delta K). Occurance of this arrhythmia, it was not confirmed whetner it was due to increased serum potassium(delta K=0.8 mEq/L) or other factors. 3. Surprisingly, fasciculation was minimal level in all cases. 4. Significance in statistical analysis did not correspond with clinical signs. 5. Succinylcholine iodide intravenous administration was not contraindicated for intubation in. burned patient.

MeSH Terms

Administration, Intravenous
Anesthesia
Arrhythmias, Cardiac
Burns*
Central Nervous System
Electrocardiography
Fasciculation
Heart Arrest
Humans
Hyperkalemia
Intubation
Muscle, Skeletal
Paralysis
Peripheral Nerve Injuries
Potassium*
Preoperative Period
Succinylcholine
Ventricular Premature Complexes
Potassium
Succinylcholine