Korean J Ophthalmol.  2014 Dec;28(6):497-499. 10.3341/kjo.2014.28.6.497.

A Case of Syphilitic Outer Retinitis Mimicking Acute Zonal Occult Outer Retinopathy

• Kim JA
• Park KH
• Woo SJ

• KMID: 2345829
• DOI: http://doi.org/10.3341/kjo.2014.28.6.497

Abstract

No abstract available.

MeSH Terms

Anti-Bacterial Agents/therapeutic use
Diagnosis, Differential
Electroretinography
Eye Infections, Bacterial/*diagnosis/drug therapy
Fluorescein Angiography
Humans
Male
Middle Aged
Penicillin G Benzathine/therapeutic use
Retinitis/*diagnosis/drug therapy
Scotoma/*diagnosis/drug therapy
Syphilis/*diagnosis/drug therapy
Syphilis Serodiagnosis
Tomography, Optical Coherence
Visual Acuity/physiology
Anti-Bacterial Agents
Penicillin G Benzathine

Figure

• 

  Fig. 1 Summary of clinical and diagnostic features. At initial visit, color fundus photography (A) and fundus f luorescein angiography (A) showed normal appearance. However, fundus autofluorescence (FAF) imaging (C) and spectral-domain optical coherence tomography (SD-OCT) (D) showed hyperfluorescence and diffuse disruption of the photoreceptor inner segment-outer segment (IS-OS) junction line (white arrowheads indicate the border of the irregular photoreceptor IS-OS junction area) in the centermost area and inferior retinal areas of macula corresponding to the area of reduced amplitudes in the multifocal electroretinography (ERG) (E). Humphrey visual field (HVF) perimetry showed that the visual field defects corresponded to SD-OCT, FAF imaging, and multifocal ERG (F). Although the photoreceptor disruption was partially restored at 3 months after treatment (G), the disruption became aggravated gradually thereafter (H), at 5 months after treatment (I), at 6 months after treatment. (J) One month after antimicrobial treatment with penicillin, restoration of the photoreceptor IS-OS junction occurred, and vision was restored to 20 / 30 in right eye. Three months after antimicrobial therapy, vision improved to 20 / 20 in right eye and SD-OCT revealed complete restoration of the photoreceptor IS-OS junction (K). Multifocal ERG (L) and HVF (M) showed nearly complete normalization of visual function.

Reference

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