Korean J Ophthalmol.  2014 Dec;28(6):493-495. 10.3341/kjo.2014.28.6.493.

A Case of Paradoxical Reaction after Treatment of Eyelid Tuberculosis

Affiliations
  • 1Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. yoonjs@yuhs.ac
  • 2Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Aged, 80 and over
Antitubercular Agents/*therapeutic use
Eyelid Diseases/drug therapy/*physiopathology
Glucocorticoids/therapeutic use
Humans
Male
Prednisolone/therapeutic use
Tuberculosis, Ocular/drug therapy/*physiopathology
Antitubercular Agents
Glucocorticoids
Prednisolone

Figure

  • Fig. 1 Representative photographs showing clinical course of the patient. (A) At initial visit left upper and lower eyelids were swollen with erythema. (B) After a month treatment of steroid, eyelid swelling and erythema was partially improved. (C) Arrow indicates acid-fast bacilli on the pathology. (D) After 3 weeks of anti-tuberculosis (anti-TB) medication, cluster and granulation formation of the upper eyelids with skin necrosis and oozing at the biopsied lesion was observed. (E) After 5 weeks of anti-TB medication, severe wound dehiscence was noted. (F) After 1 month of combined steroid and anti-TB treatment, wound dehiscence was healed and fibrosis of the upper eyelid soft tissues was observed.


Reference

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2. Onal IK, Bayraktar Y, Unal S. Paradoxical deterioration during the course of antituberculous treatment. J Natl Med Assoc. 2006; 98:954–955.
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5. Van der Meulen J, de Jong GM, Westenend PJ. Acute interstitial nephritis during rifampicin therapy can be a paradoxical response: a case report. Cases J. 2009; 2:6643.
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