131-I-BSP and Rose Bengal liver scan

Kim, Y S; Oh, K K; Choi, B S; Park, C Y

Abstract

Since Taplin started the 131I-RB liver function study in 1954, Beak and Eyler reported scanning using I-131 RBfor the first time for differentiation of etiologic factor of clinical jaundice. Recently Mamori studied about theserial blood clearance rate of liver after injection of 131I-BSP intravenously. In Yonsei University, we haveselected 131-BSP and 131I-RB liver and abdominal scanning in clinically suspicious obstructive jaundice. Weanalyzed 27 cases of 131I-BSP, RB scanning and reviewed other literature about the 131I-RB, or 131I-BSP liver andabdominal scanning. Result : 1. in normal control group, gall bladder uptake of 131I-BSP was done within 30minutes, and the colonic uptake was within 2hrs in general scanning, and suggestive of normal patency of biliarytree. 2. In Hepatocellular group of liver cirrhosis and hepatitis, diffuse decreased uptake of mottling densitiesin initial liver scan, and there had been delayed excretion in to G.B. or colon, however, there was no definitiveevidence of biliary obstruction. 3. In Hepatoma and liver abscess group, discrete cold area in initial parenchymalliver scanning, however, intestinal excretion was visualized within 2 hours and suggesting biliary patency. 4. Extrahepatic obstructive jaundice such as cholangiocarcinoma, hepatoma involving porta hepatis and choledochalcyst fail to excrete 131I-BSP, or 131I-RB into intestine and suggesting obstructive jaundice. 5. In unconfirmedjaundiced group I-131 BSP or 131I-RB show delayed but all excreted into intestine suggesting delayed biliarypatency.